Radical surgery for lingual cancer.

Radical surgery for lingual cancer.
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舌癌根治性手术。

DOI:
10.1111/j.1365-2273.1990.tb00780.x
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发表时间:
1990
期刊:
Clinical otolaryngology and allied sciences
影响因子:
--
通讯作者:
P. Karma
P. Karma
中科院分区:
--
文献类型:
--
作者:
J. Pukander;T. Karhuketo;M. Penttilä;H. Pertovaara;P. Karma

文献摘要

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本文报告1972 ~ 1985年收治的58例舌鳞癌患者的生存率。总体5年生存率为41.6%; I期为61.8%; II期为59.5%; III期为27.7%。没有病人生存超过2年时,他们的肿瘤是第四阶段的介绍。根治性颈淋巴结清扫术的5年生存率为50.7%,显著高于其他治疗(主要是局部肿瘤切除联合放疗)的13.8%(P <0.01)。同样的趋势有利于根治性手术,也看到了阶段性。45%的患者存在区域性颈部转移(35%可触及,10%隐匿),预测预后不良。T1 ~ T2期N 0组5年生存率为58.5%,显著高于有淋巴结转移组的15.1%(P <0.01)。原发肿瘤的位置不影响生存率。
The survival rates of 58 patients treated for squamous carcinoma of the tongue between 1972 and 1985 were evaluated. The overall 5-year survival rate was 41.6%; for stage I it was 61.8%; stage II 59.5%; and stage III, 27.7%. No patient survived for more than 2 years when their tumour was stage IV on presentation. A composite pull-through resection with radical neck dissection gave a 5-year survival rate of 50.7%, which was significantly (P less than 0.01) higher than the 13.8% achieved by other treatments, mainly local tumour excision combined with radiation therapy. The same trend in favour of radical surgery was also seen stage by stage. In 45% of the patients regional neck metastases (palpable in 35% and occult in 10%) were present and predicted a poor prognosis. Among T1-T2 cases the 5-year survival of 58.5% in the N0 group was significantly (P less than 0.01) higher than the 15.1% among those with nodal involvement. The location of the primary tumour did not affect the survival rates.