Brain activity during anticipation of smoking-related and emotionally positive pictures in smokers and nonsmokers: a new measure of cue reactivity.
Brain activity during anticipation of smoking-related and emotionally positive pictures in smokers and nonsmokers: a new measure of cue reactivity.
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DOI：
10.1080/14622200802412911
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发表时间：
2008-11
期刊：
影响因子：
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通讯作者：
Ashley B Parker;D. Gilbert
中科院分区：
文献类型：
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作者：
Ashley B Parker;D. Gilbert
先前的研究表明，一种被称为刺激先于消极(SPN)的脑电波模式可以指示对与动机相关的事件的预期。本研究首次使用SPN作为吸烟相关图片的激励意义的指标。情绪积极和中性的图片作为对照。该范式包括以下序列：(A)呈现一张图片(S1)500ms，(B)注视交叉3500ms，(C)第二次呈现相同图片(S2)2000ms，以及(D)另一个注视交叉表示使用不同图片的新的S1-S2试验的开始。参与者(N=24，一半吸烟者和一半不吸烟者)观看了三种类别的照片(与吸烟有关的、情绪积极的或情绪中立的)。与预测一致的是，吸烟者在预期与吸烟相关的图片时表现出明显高于中性图片的平均SPN波幅。在不吸烟的人中，与中性照片相比，SPN对吸烟照片的预期显着较小。这些发现与成瘾的激励敏感化理论以及其他条件反应和线索-反应模型是一致的。
Previous studies have shown that a brain wave pattern known as stimulus preceding negativity (SPN) can index the anticipation of motivationally relevant events. The present study was the first to use SPN as an index of the motivational significance of smoking-related pictures. Emotionally positive and neutral pictures served as controls. The paradigm involved the following sequence: (a) presentation of a picture (S1) for 500 ms, (b) a fixation cross for 3,500 ms, (c) a second presentation (S2) of the same picture for 2,000 ms, and (d) another fixation cross signifying the beginning of a new S1-S2 trial using a different picture. The participants (N = 24, half smokers and half nonsmokers) viewed pictures from three categories (smoking-related, emotionally positive, or emotionally neutral). Consistent with predictions, smokers exhibited significantly greater mean SPN amplitudes in anticipation of smoking-related pictures relative to neutral pictures. Among nonsmokers the SPN was significantly smaller in anticipation of smoking pictures compared with neutral pictures. These findings are consistent with the incentive sensitization theory of addiction and other conditioning and cue-reactivity models.