Fluorescence image-guided surgery of brain tumors: Explained step-by-step

Fluorescence image-guided surgery of brain tumors: Explained step-by-step
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DOI:
10.1016/j.pdpdt.2008.11.003
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发表时间:
2008-12-01
影响因子:
3.3
通讯作者:
Eljamel, M. Sam
Eljamel, M. Sam
中科院分区:
医学3区
文献类型:
--
作者:
Eljamel, M. Sam

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荧光图像引导手术(FIGS)和荧光引导切除术(FGR)是用于最大限度地切除肿瘤并最大限度地减少附带损伤的手术技术。图1和FGR结合了联合收割机术前光敏剂施用和手术期间的荧光检测,通过使用适当的波长照射手术区域并经由长通滤光器观察荧光,所述长通滤光器允许外科医生看到荧光肿瘤。商业上可获得的技术已经导致65%的患者的增强型脑肿瘤的总体全切除,而在标准白色光手术下仅为35%。这是FIGIN大脑技术的分步概要。(C)2009爱思唯尔有限公司版权所有。
Fluorescence image-guided surgery (FIGS) and fluorescence-guided resection (FGR) are surgical techniques used to maximise tumor excision and minimise collateral damage. FIGS and FGR combine preoperative photosensitizer-administration and fluorescence detection during surgery, by illumination of the surgical field using the appropriate wavelength and observing the fluorescence via a long-pass filter that allows fluorescent tumor to be seen by the surgeon. Commercially available technology has led to gross total resection of enhancing brain tumors in 65% of patients compared to merely 35% under standard white light surgery. This is a step-by-step synopsis of the techniques of FIGS in brain. (C) 2009 Elsevier B.V. All rights reserved.