iPSC-Derived Organs In Vivo: Challenges and Promise.

iPSC-Derived Organs In Vivo: Challenges and Promise.
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DOI:
10.1016/j.stem.2017.12.003
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发表时间:
2018-01
期刊:
影响因子:
23.9
通讯作者:
Fabian P. Suchy;Tomoyuki Yamaguchi;H. Nakauchi
Fabian P. Suchy;Tomoyuki Yamaguchi;H. Nakauchi
中科院分区:
医学1区
文献类型:
--
作者:
Fabian P. Suchy;Tomoyuki Yamaguchi;H. Nakauchi

文献摘要

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将iPSC移植到另一个物种的胚胎中可以产生用于基础研究和转化应用的功能器官。我们讨论了前瞻性的方法,并解决了在体内产生iPSC衍生的人类器官的关键挑战。
Transplanting iPSCs into the embryos of another species can generate functional organs for basic research and translational applications. We discuss forward-looking approaches and address key remaining challenges of generating iPSC-derived human organsin vivo.