A new pseudo C2-symmetric tertiary diamine for the enantioselective addition of MeLi to aromatic imines
A new pseudo C2-symmetric tertiary diamine for the enantioselective addition of MeLi to aromatic imines
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DOI：
10.1016/j.tetasy.2006.03.026
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发表时间：
2006-04-03
影响因子：
--
通讯作者：
Alexakis, Alexandre
中科院分区：
文献类型：
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作者：
Gille, Segolene;Cabello, Noemi;Alexakis, Alexandre
以(1S,2S)-(+)-伪麻黄碱为原料合成了一种新的伪c -2对称叔胺，并对MeLi与芳香亚胺的对映选择性加成进行了实验。与先前在相同反应中成功使用的类似c2对称配体的比较研究表明，该新型二胺具有相当的选择性和更好的反应活性。(c) 2006 Elsevier Ltd.版权所有。
A new tertiary pseudo C-2-symmetric 1,2-diamine derived from (1S,2S)-(+)-pseudoephedrine was synthesized and tested in the enantio selective addition of MeLi to aromatic imines. A comparative study with the analogous C2-symmetric ligand successfully used previously in the same reaction showed comparable selectivity and better reactivity for this novel diamine. (c) 2006 Elsevier Ltd. All rights reserved.