Rapidly switchable matrix-assisted laser desorption/ionization and electrospray quadrupole-time-of-flight mass spectrometry for protein identification
Rapidly switchable matrix-assisted laser desorption/ionization and electrospray quadrupole-time-of-flight mass spectrometry for protein identification
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DOI：
10.1016/s1044-0305(00)00114-8
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发表时间：
2000-06-01
影响因子：
3.2
通讯作者：
Chait, BT
中科院分区：
文献类型：
--
作者：
Krutchinsky, AN;Zhang, WZ;Chait, BT
我们描述了一个新的接口的原型四极-四极-飞行时间（TOF）质谱仪（半人马座，Sciex），允许快速切换电喷雾电离（ESI）和基质辅助激光解吸/电离（MALDI）的操作模式。两种模式下的仪器性能相当（即，分辨率类似于10，000 FWHM，质量准确度
We describe a new interface for a prototype quadrupole-quadrupole-time-of-flight (TOF) mass spectrometer (Centaur, Sciex) that allows rapid switching between electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) modes of operation. Instrument performance in both modes is comparable (i.e., resolution similar to 10,000 FWHM, mass accuracy