Feasibility and Accuracy of a Computer-Assisted Self-Interviewing Instrument to Ascertain Prior Immunization With Human Papillomavirus Vaccine by Self-Report: Cross-Sectional Analysis
Feasibility and Accuracy of a Computer-Assisted Self-Interviewing Instrument to Ascertain Prior Immunization With Human Papillomavirus Vaccine by Self-Report: Cross-Sectional Analysis
复制标题
DOI：
10.2196/16487
复制
发表时间：
2020-01-01
影响因子：
3.2
通讯作者：
Niccolai, Linda M.
中科院分区：
文献类型：
--
作者：
Oliveira, Carlos R.;Avni-Singer, Lital;Niccolai, Linda M.
背景：确定人乳头瘤病毒（HPV）疫苗的既往免疫史可能具有挑战性和资源密集型。计算机辅助的自我访谈工具有可能解决自我报告的一些挑战，也可能减少与确定免疫状况有关的时间、成本和努力。目的：本研究评估计算机辅助自我访谈工具确定患者HPV疫苗免疫史的可行性和准确性。方法：我们开发了一项调查和一个基于网络的数据收集系统，使用计算机辅助自我访谈来确定自我报告的HPV疫苗免疫史。我们在一项正在进行的HPV疫苗研究中招募的成年女性样本中实施了该仪器。审查了以前护理来源的疫苗记录，以核实报告的免疫史。结果：在312名自我报告HPV疫苗免疫史的参与者中，几乎所有（99%）的人都能使用计算机辅助的自我访谈工具。中位调查完成时间为10分钟（IQR 7-17）。自我报告的准确性为84%，敏感性为89%，特异性为80%，阴性预测值为92%。结论：我们发现使用计算机辅助的自我访谈工具收集HPV疫苗免疫史是可行的。这种方法很可能被成年女性接受，并且在临床研究中相当准确。
Background: Ascertaining history of prior immunization with human papillomavirus (HPV) vaccine can be challenging and resource-intensive. Computer-assisted self-interviewing instruments have the potential to address some of the challenges of self-reporting, and may also reduce the time, costs, and efforts associated with ascertaining immunization status.Objective: This study assesses both the feasibility and the accuracy of a computer-assisted self-interviewing instrument to ascertain a patient's history of immunization with the HPV vaccine.Methods: We developed both a survey and a Web-based data collection system using computer-assisted self-interviewing to ascertain self-reported HPV vaccine immunization history. We implemented the instrument in a sample of adult women enrolled in an ongoing study of the HPV vaccine. Vaccine records from prior sources of care were reviewed to verify reported immunization history.Results: Among the 312 participants who provided HPV vaccine immunization history by self-report, almost all (99%) were able to do so using the computer-assisted self-interviewing instrument. The median survey completion time was 10 minutes (IQR 7-17). The accuracy of self-report was 84%, sensitivity was 89%, specificity was 80%, and the negative predictive value was 92%.Conclusions: We found that it is feasible to collect a history of immunization with the HPV vaccine using a computer-assisted self-interviewing instrument. This approach is likely to be acceptable to adult women and is reasonably accurate in a clinical research setting.