Smart Antibacterial Surface Made by Photopolymerization
Smart Antibacterial Surface Made by Photopolymerization
复制标题
光聚合智能抗菌表面
DOI：
10.1021/acsami.6b09343
复制
发表时间：
2016
影响因子：
9.5
通讯作者：
Nie Jun
中科院分区：
文献类型：
--
作者：
Yang Haitao;Li Guofeng;Stansbury Jeffrey W.;Zhu Xiaoqun;Wang Xing;Nie Jun
基于光聚合技术的应用，提出了一种简便可靠的原位制备银纳米粒子（AgNPs）的方法，该方法可在PNIPAAm功能表面上制备无污染的抗菌薄膜。通过透射电子显微镜（TEM）、X射线光电子能谱（XPS）、水接触角和热重分析（TGA）对表面性能进行了表征。针对大肠杆菌测试了表面的抗菌和释放特性：在37 °C（高于PNIPAAm的LCST）下，功能膜促进细菌的附着，然后细菌被AgNP杀死。将温度改变为4 °C（低于LCST），膨胀的PNIPAAm链导致死细菌的释放。结果表明，AgNPs/PNIPAAm杂化表面提供了一个“智能”的抗菌能力，响应于环境温度的变化。
On the basis of the use of photopolymerization technology, a facile and reliable method for in situ preparation of silver nanoparticles (AgNPs) within PNIPAAm functional surfaces is presented as a means to achieve nonfouling, antibacterial films. The surface properties were characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), water contact angle, and thermogravimetric analysis (TGA). The antibacterial and release properties of the surfaces were tested against E.coli: at 37 °C (above the LCST of PNIPAAm), the functional films facilitated the attachment of bacteria, which were then killed by the AgNPs. Changing temperature to 4 °C (below the LCST), swollen PNIPAAm chains led the release of dead bacteria. The results showed that AgNPs/PNIPAAm hybrid surfaces offer a “smart” antibacterial capability in response to the change of environmental temperature.