Differences in Lung and Lobe Volumes between Supine and Standing Positions Scanned with Conventional and Newly Developed 320-Detector-Row Upright CT: Intra-Individual Comparison
Differences in Lung and Lobe Volumes between Supine and Standing Positions Scanned with Conventional and Newly Developed 320-Detector-Row Upright CT: Intra-Individual Comparison
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DOI：
10.1159/000507265
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发表时间：
2020-08-01
期刊：
影响因子：
3.7
通讯作者：
Jinzaki, Masahiro
中科院分区：
文献类型：
--
作者：
Yamada, Yoshitake;Yamada, Minoru;Jinzaki, Masahiro
背景：迄今为止，没有临床研究比较了仰卧位和站立位之间的单侧肺或肺叶体积。目的：比较这两种位置之间的计算机断层扫描（CT）上的肺/肺叶体积，并评估肺功能测试（PFTs）上的总肺体积和总肺容量（TLC）之间的相关性。方法：32名无症状志愿者在深吸气屏气期间接受了常规CT（仰卧位）和直立CT（站立位），并在同一天接受了PFTs。我们在CT上测量了每个位置的肺/肺叶体积。结果：立位时全肺、右肺、右上叶、右下叶、左肺、左上叶、左下叶体积分别增加10.9%、10.3%、8.6%、14.6%、11.6%、7.1%、16.0%，均显著大于仰卧位（p < 0.0001）。两个位置之间的右中叶体积相似（p= 0.16）。组内相关系数之间的协议在仰卧位/站立位的CT和TLC上PFT的肺总体积分别为0.891/0.938，respectively：虽然体积的双肺上下叶和双肺显着大于在仰卧位的立场，与下叶显示较大的变化，右中叶的体积并没有显着变化之间的位置。立位CT显示的肺总体积与PFT显示的TLC更接近。
Background:No clinical studies to date have compared unilateral lung or lobe volumes between the supine and standing positions.Objectives:To compare lung/lobe volumes on computed tomography (CT) between these two positions and evaluate the correlation between the total lung volume and total lung capacity (TLC) on pulmonary function tests (PFTs).Methods:Thirty-two asymptomatic volunteers underwent both conventional CT (supine position) and upright CT (standing position), during deep inspiration breath-hold, and PFTs on the same day. We measured lung/lobe volumes on CT in each position. Pairedttests were used for statistical analysis.Results:The volumes of the total lung (10.9% increase), right lung (10.3% increase), right upper lobe (8.6% increase), right lower lobe (14.6% increase), left lung (11.6% increase), left upper lobe (7.1% increase), and left lower lobe (16.0% increase) were significantly greater in the standing position than in the supine position (allp< 0.0001). The right middle lobe volume was similar between the two positions (p= 0.16). Intraclass correlation coefficients for agreement between total lung volumes on CT in the supine/standing positions and the TLC on PFT were 0.891/0.938, respectively.Conclusions:While the volumes of the bilateral upper and lower lobes and bilateral lungs were significantly greater in the standing than in the supine position, with lower lobes showing larger changes, the right middle lobe volume did not change significantly between positions. The total lung volume on upright CT in the standing position was more similar to TLC on PFT than that in the supine position.