The development and preliminary validation of a scale measuring the impact of syncope on quality of life

The development and preliminary validation of a scale measuring the impact of syncope on quality of life
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DOI:
10.1093/europace/eup106
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发表时间:
2009-10-01
期刊:
影响因子:
6.1
通讯作者:
Sheldon, Robert
Sheldon, Robert
中科院分区:
医学2区
文献类型:
--
作者:
Rose, Marianne Sarah;Koshman, Mary-Lou;Sheldon, Robert

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为了建立一个简明的晕厥特异性健康相关生活质量测量方法,114例晕厥患者完成了一份48项问卷,该问卷来自生活质量的通用测量方法(EQ-5D)、晕厥功能状态问卷、抑郁量表(CES-D)和既往症状。根据这些数据,使用临床影响方法得出晕厥对生活质量(ISQL)的12项影响。ISQL与前一年的晕厥发作次数相关(r = 0.35),自感健康状况(r = -0.55),SFSQ的三个评分:[减值(r = 0.77),恐惧和担忧(r = 0.72)、晕厥功能障碍(r = 0.82)和抑郁(r = 0.62)],说明了其与这些概念的收敛效度。在EQ-5D上显示生活质量降低的患者与未显示生活质量降低的患者之间存在明显的已知组间差异。ISQL评分与年龄、性别无显著相关性。与前一年相比,ISQL评分与前一年发作频率的相关性更好。ISQL是晕厥对生活质量影响的一种简单有效的测量方法。它测量损伤、恐惧、抑郁和身体限制,并与近期晕厥频率相关。
To develop a brief syncope-specific measure of health-related quality of life.One hundred and fourteen patients with syncope completed a 48-item questionnaire derived from a generic measure of quality of life (the EQ-5D), the Syncope Functional Status Questionnaire, a depression scale (the CES-D) and historical symptoms. From these, clinical impact methodology was used to derive 12-item Impact of Syncope on Quality of Life (ISQL). The ISQL correlated with the number of syncopal spells in the previous year (r = 0.35), self-perceived health status (r = -0.55), the three scores from the SFSQ: [impairment (r = 0.77), fear and worry (r = 0.72), syncope dysfunction (r = 0.82), and depression (r = 0.62)], illustrating its convergent validity with these concepts. Known group differences were evident between patients who exhibited reduced quality of life on the EQ-5D and those who did not. There was no significant correlation between ISQL score and age or gender. ISQL score correlated better with the frequency of spells in the previous year than years prior to the previous year.The ISQL is a brief valid measure of the impact of syncope on quality of life. It measures impairment, fear, depression, and physical limitations, and correlates with recent syncope frequency.