Clustering of eating disorder symptoms in a general population female twin sample: a latent class analysis
Clustering of eating disorder symptoms in a general population female twin sample: a latent class analysis
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DOI：
10.1017/s0033291707000505
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发表时间：
2007-08-01
影响因子：
6.9
通讯作者：
Heath, Andrew C.
中科院分区：
文献类型：
--
作者：
Duncan, Alexis E.;Bucholz, Kathleen Keenan;Heath, Andrew C.
背景。先前的研究报道，目前的DSM-IV饮食失调（ED）标准没有充分描述ED的症状。本研究的目的是使用潜在类分析（LCA）检查普通人群样本中ED症状的聚类。使用LCA分析了3723名年轻女性双胞胎（平均年龄22岁）的ED症状，并通过外部验证器比较了ED和其他共病精神诊断、物质使用障碍（SUDS）和自杀倾向。最优解由五个潜在类别组成，其特征为：(1)不受影响；(2)增重低；(3)有关重量；(4)节食者;与未受影响组和低增重组相比，ED组的成员有更高的共病性精神障碍、sud和自杀率，与体重关注组和节食组相比，ED组的成员有更高的自杀率和重度抑郁症，这主要是在当前的身体质量指数（BMI）方面存在差异。节食班的成员比体重关注班的成员更容易超重和肥胖，而体重不足的可能性更小。大多数诊断为ED的女性被分配到ED组，在ED组成员中发现有ED和没有ED的差异很小。该结果进一步证明，许多具有明显ED精神病理的女性没有被DSM-IV ED分类识别。
Background. Previous studies have reported that the current DSM-IV eating disorder (ED) criteria do not adequately describe ED syrnptomatology. The objective of the current study was to examine the clustering of ED symptoms in a general population sample using latent class analysis (LCA).Method. ED symptoms from 3723 female young adult twins (mean age 22) were analyzed using LCA, and resulting classes were compared on external validators reflecting ED and other co-morbid psychiatric diagnoses, substance use disorders (SUDS), and suicidality.Results. The optimal solution consisted of five latent classes characterized as: (1) Unaffected; (2) Low Weight Gain; (3) Weight Concerned; (4) Dieters; and (5) ED. Members of the ED class had significantly higher prevalence of co-morbid psychiatric disorders, SUDs, and suicidality than the Unaffected and Low Weight Gain classes, and elevated rates of suicidality and major depression compared to the Weight Concerned and Dieter classes, which differed from each other primarily in terms of current body mass index (BMI). Dieter class members were more likely to be overweight and obese and less likely to be underweight than Weight Concerned class members. The majority of women with an ED diagnosis were assigned to the ED class, and few differences were found between ED class members with and without an ED diagnosis.Conclusions. The results add to the evidence that many women with significant ED psychopathology are not being identified by the DSM-IV ED categories.