Label-free Biosensing Based on Single Gold Nanostars as Plasmonic Transducers
Label-free Biosensing Based on Single Gold Nanostars as Plasmonic Transducers
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DOI：
10.1021/nn100760f
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发表时间：
2010-11-01
期刊：
影响因子：
17.1
通讯作者：
Feldmann, Jochen
中科院分区：
文献类型：
--
作者：
Dondapati, Srujan K.;Sau, Tapan K.;Feldmann, Jochen
金纳米星为单纳米颗粒无标记生物传感提供高灵敏度。纳米星呈现多个等离子体共振，其中较低能量的等离子体共振，对应着纳米星的尖端和核心尖端相互作用对环境变化最敏感链霉抗生物素蛋白分子在与单独的生物素修饰的金纳米星结合时通过等离子体共振中的光谱位移检测到。尖端等离子体共振约为2 3nm（5 3meV）
Gold nanostars provide high sensitivity for single nanoparticle label free biosensing The nanostars present multiple plasmon resonances of which the lower energy ones, corresponding to the nanostar tips and core-tip interactions are the most sensitive to environmental changes streptavidin molecules are detected upon binding to individual biotin modified gold nanostars by spectral shifts in the plasmon resonances Concentrations at low as 0 1 nM produce a shift of the tip related plasmon resonances of about 2 3 nm (5 3 meV)