The combinational use of CRISPR/Cas9-based gene editing and targeted toxin technology enables efficient biallelic knockout of the α-1,3-galactosyltransferase gene in porcine embryonic fibroblasts.

The combinational use of CRISPR/Cas9-based gene editing and targeted toxin technology enables efficient biallelic knockout of the α-1,3-galactosyltransferase gene in porcine embryonic fibroblasts.
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结合使用基于 CRISPR/Cas9 的基因编辑和靶向毒素技术,可以实现猪高效成纤维细胞中 α-1,3-半乳糖基转移胚胎酶基因的双等位基因敲除。

DOI:
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发表时间:
2014
影响因子:
3.9
通讯作者:
Satoshi Watanabe
Satoshi Watanabe
中科院分区:
医学3区
文献类型:
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作者:
Masahiro Sato;Kazuchika Miyoshi;Yozo Nagao;Yohei Nishi;Masato Ohtsuka;Shingo Nakamura;Takayuki Sakurai;Satoshi Watanabe

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