High frame-rate simultaneous bilateral breast DCE-MRI
High frame-rate simultaneous bilateral breast DCE-MRI
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DOI：
10.1002/mrm.21114
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发表时间：
2007-01-01
影响因子：
3.3
通讯作者：
Song, Hee Kwon
中科院分区：
文献类型：
--
作者：
Dougherty, Lawrence;Isaac, Gamaliel;Song, Hee Kwon
开发并评估了一种用于3D动态对比增强（DCE）-MRI的同时双侧反射方法。使用RF平板激发脉冲的双侧带调制，同时选择了包括两个乳房的不连续体积。切片相编码步骤的数量被缩采样了2倍，并使用感官处理来删除从一个体积到另一个体积的结果信号。使用动态k-空道加权对比度（KWIC）时间滤波重建的交错径向采集进行平面编码。图像分辨率为0.5 x 0.5 x 3.0 mm（3），两种乳房的有效时间分辨率为15 s。与传统双侧MR乳房扫描相比，这是感官编码的2倍加速度，这是一个16倍的加速因子。对这些方法的初步评估是对出现明显或乳房X线乳腺X射线异常的一群女性进行的。在进行的54项双边检查中，有45例总共发现了73个异常。在其中11例中，对侧乳房有一个重大发现。可以同时获得两种乳房的DCE图像，从而产生高分辨率图像以及对比度动力学的快速采样。
A simultaneous bilateral back-projection method for 3D dynamic contrast-enhanced (DCE)-MRI of the breasts was developed and evaluated. Using a double-side band modulation of the RF slab excitation pulse, discontinuous volumes that included both breasts were simultaneously selected. The number of slice phase-encoding steps was undersampled by a factor of 2, and the resulting signal aliasing from one volume to the other was removed using SENSE processing. In-plane encoding was performed with an interleaved radial acquisition reconstructed using dynamic k-space-weighted image contrast (KWIC) temporal filtering. Image resolution was 0.5 x 0.5 x 3.0 mm(3) with an effective temporal resolution of 15 s for both breast volumes. Combined with the 2x acceleration from SENSE encoding, this is a 16x acceleration factor over a conventional MR bilateral breast scan. An initial evaluation of these methods was performed on a cohort of women who presented with palpable or mammographically visible breast abnormalities. A total of 73 abnormalities were found in 45 of the 54 bilateral examinations that were performed. In 11 of these cases there was a significant finding in the contralateral breast. DCE images of both breasts can be acquired simultaneously, resulting in high-resolution images as well as rapid sampling of the contrast kinetics.