Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance - Are they interchangeable?
Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance - Are they interchangeable?
复制标题
DOI：
10.1053/euhj.2000.2011
复制
发表时间：
2000-08-01
影响因子：
39.3
通讯作者：
Pennell, DJ
中科院分区：
文献类型：
--
作者：
Bellenger, NG;Burgess, MI;Pennell, DJ
目的前瞻性比较M型超声心动图(ECHO)、二维超声心动图(2D ECHO)、核素心动图和心血管磁共振心动图测定慢性稳定性心力衰竭患者左心室容量和射血分数的一致性。重要的是要知道每种技术的结果是否可以互换，从而知道利用一种技术在心力衰竭方面的大型研究结果如何应用于另一种技术。一些研究将心血管磁共振与ECHO或放射性核素脑室造影进行了比较，但很少有心力衰竭患者，也没有研究将这些技术与目前快速屏气采集的心血管磁共振进行比较。方法与结果参加圣诞研究的52例慢性稳定型心力衰竭患者在4周内接受了M型回声、2D回波、放射性核素脑室造影和心血管磁共振检查。扫描是由三个核心实验室的一名研究人员以盲目方式独立分析的。在超声心动图中，86%的超声心动图图像质量足以用M型超声心动图测量左心室射血分数，而用二维Simpson双平面分析法只有69%能获得足够的图像质量。52例患者均能耐受放射性核素脑室造影和心血管磁共振检查，扫描结果均可分析。M型立方体法测得的平均左心室射血分数为39+/-16%，Teichholz-M型法测得的平均左心室射血分数为29+/-15%。二维超声心动图测得的平均射血分数为31+/-10%，核素心动图测得的平均射血分数为24+/-9%，心血管磁共振测得的平均射血分数为30+/-11。
Aims To prospectively compare the agreement of left ventricular volumes and ejection fraction by M-mode echocardiography (echo), 2D echo, radionuclide ventriculography and cardiovascular magnetic resonance performed in patients with chronic stable heart failure. It is important to know whether the results of each technique are interchangable, and thereby how the results of large studies in heart failure utilizing one technique can be applied using another. Some studies have compared cardiovascular magnetic resonance with echo or radionuclude ventriculography but few contain patients with heart failure and none have compared these techniques with the current fast breath-hold acquisition cardiovascular magnetic resonance.Methods and Results Fifty two patients with chronic stable heart failure taking part in the CHRISTMAS Study, underwent M-mode echo, 2D echo, radionuclude ventriculography and cardiovascular magnetic resonance within 4 weeks. The scans were analysed independently in blinded fashion by a single investigator at three core laboratories. Of the echocardiograms, 86% had sufficient image quality to obtain left ventricular ejection fraction by M-mode method, but only 69% by 2D Simpson's biplane analysis. All 52 patients tolerated the radionuclude ventriculography and cardiovascular magnetic resonance, and all these scans were analysable. The mean left ventricular ejection fraction by M-mode cube method was 39 +/- 16% and 29 +/- 15% by Teichholz M-mode method. The mean left ventricular ejection fraction by 2D echo Simpson's biplane was 31 +/- 10%, by radionuclude ventriculography was 24 +/- 9% and by cardiovascular magnetic resonance was 30 +/- 11. All the mean left ventricular ejection fractions by each technique were significantly different from all other techniques (P