Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on Acute Admissions at the Emergency and Cardiology Departments Across Europe.
Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on Acute Admissions at the Emergency and Cardiology Departments Across Europe.
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DOI：
10.1016/j.amjmed.2020.08.043
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发表时间：
2021-04
期刊：
影响因子：
--
通讯作者：
Ponikowski P
中科院分区：
文献类型：
--
作者：
Sokolski M;Gajewski P;Zymliński R;Biegus J;Berg JMT;Bor W;Braunschweig F;Caldeira D;Cuculi F;D'Elia E;Edes IF;Garus M;Greenwood JP;Halfwerk FR;Hindricks G;Knuuti J;Kristensen SD;Landmesser U;Lund LH;Lyon A;Mebazaa A;Merkely B;Nawrocka-Millward S;Pinto FJ;Ruschitzka F;Semedo E;Senni M;Sepehri Shamloo A;Sorensen J;Stengaard C;Thiele H;Toggweiler S;Tukiendorf A;Verhorst PM;Wright DJ;Zamorano P;Zuber M;Narula J;Bax JJ;Ponikowski P
我们评估了严重急性呼吸综合征冠状病毒2（SARS-COV-2）大流行是否与欧洲各中心急性心血管入院模式的变化相关。我们在12个国家的15个中心建立了一个多中心、多国、泛欧观察性登记研究。于2019冠状病毒病爆发期间的1个月期间，急诊科及心脏科的所有连续急性入院人数与2019年的1个月期间进行比较。将心内科的急性入院分为5大类：急性冠脉综合征、急性心力衰竭、心律失常、肺栓塞和其他。收集并分析了54，331例患者的数据。9家中心提供了急诊科急性入院的数据，包括50，384例患者：2020年为20，226例，2019年为30，158例（发病率比[IRR]和95%置信区间[95%CI]：0.66 [0.58-0.76]）。与2019年相比，2020年急诊科的死亡风险更高（比值比[OR]，95%CI：4.1 [3.0-5.8]，P < 0.0001）。所有15家中心均提供了急性心脏病科入院数据：2020年为3007例患者，2019年为4452例患者; IRR（95%CI）：0.68（0.64-0.71）。2020年，IRR（95%CI）的入院人数较少：急性冠脉综合征：0. 68（0. 63 - 0. 73）;急性心力衰竭：0. 65（0. 58 - 0. 74）;心律失常：0. 66（0. 60 - 0. 72）;其他：0. 68（0. 62 - 0. 76）。我们发现，2020年肺栓塞入院率相对较高：比值比（95%CI）：1.5（1.1-2.1），P = 0.02。在急性冠状动脉综合征患者中，不稳定型心绞痛入院率较低：0.79（0.66-0.94）;非ST段抬高型心肌梗死：0.56（0.50-0.64）; ST段抬高型心肌梗死：0.78（0.68-0.89）。在COVID-19爆发期间，欧洲中心的急性心血管入院人数减少。此外，急诊科收治的患者较少，急诊科的死亡风险高出4倍。
We evaluated whether the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) pandemic was associated with changes in the pattern of acute cardiovascular admissions across European centers. We set-up a multicenter, multinational, pan-European observational registry in 15 centers from 12 countries. All consecutive acute admissions to emergency departments and cardiology departments throughout a 1-month period during the COVID-19 outbreak were compared with an equivalent 1-month period in 2019. The acute admissions to cardiology departments were classified into 5 major categories: acute coronary syndrome, acute heart failure, arrhythmia, pulmonary embolism, and other. Data from 54,331 patients were collected and analyzed. Nine centers provided data on acute admissions to emergency departments comprising 50,384 patients: 20,226 in 2020 compared with 30,158 in 2019 (incidence rate ratio [IRR] with 95% confidence interval [95%CI]: 0.66 [0.58-0.76]). The risk of death at the emergency departments was higher in 2020 compared to 2019 (odds ratio [OR] with 95% CI: 4.1 [3.0-5.8], P < 0.0001). All 15 centers provided data on acute cardiology departments admissions: 3007 patients in 2020 and 4452 in 2019; IRR (95% CI): 0.68 (0.64-0.71). In 2020, there were fewer admissions with IRR (95% CI): acute coronary syndrome: 0.68 (0.63-0.73); acute heart failure: 0.65 (0.58-0.74); arrhythmia: 0.66 (0.60-0.72); and other: 0.68(0.62-0.76). We found a relatively higher percentage of pulmonary embolism admissions in 2020: odds ratio (95% CI): 1.5 (1.1-2.1), P = 0.02. Among patients with acute coronary syndrome, there were fewer admissions with unstable angina: 0.79 (0.66-0.94); non-ST segment elevation myocardial infarction: 0.56 (0.50-0.64); and ST-segment elevation myocardial infarction: 0.78 (0.68-0.89). In the European centers during the COVID-19 outbreak, there were fewer acute cardiovascular admissions. Also, fewer patients were admitted to the emergency departments with 4 times higher death risk at the emergency departments.
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影响因子：
3
作者：
Huet, Fabien;Prieur, Cyril;Roubille, Francois
通讯作者：
Roubille, Francois
影响因子：
39.3
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Indolfi, Ciro
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39.3
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影响因子：
3.3
作者：
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通讯作者：
White, Harvey D.
影响因子：
39.3
作者：
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通讯作者：
Luis Zamorano, Jose