Therapy and prognosis of tumors of the genitourinary tract after kidney transplantation

Therapy and prognosis of tumors of the genitourinary tract after kidney transplantation
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DOI:
10.1016/j.transproceed.2005.03.061
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发表时间:
2005-06-01
影响因子:
0.9
通讯作者:
Spiegel, HU
Spiegel, HU
中科院分区:
医学4区
文献类型:
--
作者:
Diller, R;Gruber, A;Spiegel, HU

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肾移植受者中泌尿生殖道肿瘤的发病率增加。从1979年到2001年,所有接受肾移植的患者都有其基础疾病和初始免疫抑制的记录。对发生泌尿生殖道恶性肿瘤的患者进行肿瘤类型、位置、分期、肿瘤治疗和临床病程评估。在此期间,1804例患者接受了2068例肾移植。34例患者有39个泌尿生殖系统肿瘤。1例患者失访。有15名患者的18个肾细胞癌(其中一个是多灶性的):6个有7个移行细胞癌; 6个,前列腺癌; 6个,女性生殖道肿瘤(1个也有肾细胞癌);和2个,腺瘤。大多数肿瘤是在早期诊断出来的(
There is an increased incidence of tumors of the genitourinary tract among kidney graft recipients. From 1979 to 2001, all patients who received kidney transplants had records of both their underlying diseases and their initial immunosuppression. Patients who developed a genitourinary tract malignancy were evaluated for tumor type, location, stage, tumor therapy and clinical course. During this period, 1804 patients underwent 2068 kidney transplantations. Thirty-four patients had 39 tumors of genitourinary origin. One patient was lost to follow-up. There were 15 patients with 18 renal cell carcinomas (one of them multifocal): six had seven transitional cell carcinomas; six, prostatic carcinoma; six, tumor of the female genital tract (one also had a renal cell carcinoma); and two, a seminoma. Most tumors were diagnosed in their early stages (