Articular cartilage defects detected with 3D water-excitation true FISP: Prospective comparison with sequences commonly used for knee imaging
Articular cartilage defects detected with 3D water-excitation true FISP: Prospective comparison with sequences commonly used for knee imaging
复制标题
DOI：
10.1148/radiol.2451060990
复制
发表时间：
2007-10-01
期刊：
影响因子：
19.7
通讯作者：
Hodler, Juerg
中科院分区：
文献类型：
--
作者：
Duc, Sylvain R.;Pfirrmann, Christian W. A.;Hodler, Juerg
目的：为了前瞻性地比较三维（3D）水激发（WE）真快速成像与稳态进动（FISP）在诊断关节软骨缺损的准确性与常用的序列来成像膝关节，与关节镜或手术作为参考标准。材料和方法：本研究方案是机构审查委员会批准。获得所有患者的书面知情同意书。29例患者的30个膝关节（平均年龄56岁;范围，18-86岁）进行前瞻性评价，采用矢状面3D WE真FISP，两种切片厚度（1.7 mm [真实FISP薄]和3.0 mm [真实FISP厚]），二维（2D）中等加权自旋回波，脂肪饱和，2D快速短反转时间反转恢复，3D WE双回波稳态，和3D脂肪饱和的快速低角度镜头序列。在磁共振图像上和手术过程中使用改良的Noyes评分系统对腕关节缺损进行分级。计算对比噪声比（CNR）和CNR效率。评估了敏感性、特异性和准确性。观察者之间的一致性通过kappa统计确定，定量结果通过Wilcoxon符号秩检验进行评估。3D WE True FISPthick的性能（阅片者1的敏感性、特异性和准确性分别为52%、93%和71%，阅片者2的敏感性、特异性和准确性分别为65%、88%和76%）和3D WE真FISPthin（阅片者1的敏感性、特异性和准确性分别为58%、94%和75%，阅片者2的敏感性、特异性和准确性分别为63%、80%和71%）序列在检测限制性缺陷方面与其他序列没有差异。三维WE真FISP序列有显着（P < .0033）更高的CNR和CNR效率之间的软骨和流体比相应的序列具有相同的切片thickness.Conclusion：三维WE真FISP使关节液和关节软骨之间的高对比度和诊断性能，是与标准序列相媲美。
Purpose: To prospectively compare the accuracy of three-dimensional (3D) water-excitation (WE) true fast imaging with steady-state precession (FISP) in the diagnosis of articular cartilage defects with that of sequences commonly used to image the knee, with arthroscopy or surgery as the reference standard.Materials and Methods: This study protocol was institutional review board approved. Written informed consent was obtained from all patients. Thirty knees in 29 patients (mean age, 56 years; range, 18-86 years) were prospectively evaluated by using sagittal 3D WE true FISP with two section thicknesses (1.7 mm [true FISPthin] and 3.0 mm [true FISPthick]), two-dimensional (2D) intermediate-weighted spin-echo with fat saturation, 2D fast short inversion time inversion-recovery, 3D WE double-echo steady-state, and 3D fat-saturated fast low-angle shot sequences. Cartilage defects were graded on magnetic resonance images and during surgery with a modified Noyes scoring system. Contrast-to-noise ratio (CNR) and CNR efficiency were calculated. Sensitivity, specificity, and accuracy were assessed. Inter-observer agreement was determined with kappa statistics, and quantitative results were evaluated with the Wilcoxon signed rank test.Results: The performance of 3D WE true FISPthick (sensitivity, specificity, and accuracy, respectively, were 52%, 93%, and 71% for reader 1 and 65%, 88%, and 76% for reader 2) and 3D WE true FISPthin (sensitivity, specificity, and accuracy, respectively, were 58%, 94%, and 75% for reader 1 and 63%, 80%, and 71% for reader 2) sequences was no different than that of other sequences in the detection of circumscribed defects. Three-dimensional WE true FISP sequences had a significantly (P < .0033) higher CNR and CNR efficiency between cartilage and fluid than the corresponding sequences with the same section thickness.Conclusion: Three-dimensional WE true FISP enables high contrast between joint fluid and articular cartilage and a diagnostic performance that is comparable with that of standard sequences.