Numerical studies of intermolecular multiple quantum coherences: High-resolution NMR in inhomogeneous fields and contrast enhancement in MRI
Numerical studies of intermolecular multiple quantum coherences: High-resolution NMR in inhomogeneous fields and contrast enhancement in MRI
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DOI：
10.1006/jmre.2000.2096
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发表时间：
2000-09-01
影响因子：
2.2
通讯作者：
Warren, WS
中科院分区：
文献类型：
--
作者：
Garrett-Roe, S;Warren, WS
一种快速、高效的数值算法用于研究分子间零量子相干（izqc）和双量子相干（idqc）的两种应用，这两种应用对磁化的三维结构很重要：非均匀场的高分辨率核磁共振和MRI的对比度增强。对多达200万个耦合体积单元（256 x 256 x 32）的模拟表明，izqc可以在非均匀场系统的间接检测维度中显着缩小线宽，并探索了非均匀场的形状和方向的影响。此外，本研究表明，来自iZQC和iDQC的CRAZED脉冲序列的MR图像包含了基本的新对比度，并且改进的CRAZED脉冲序列（modCRAZED）可以从化学不等效自旋中分离出对比度。(C) 2000年学术出版社。
A fast, efficient numerical algorithm is used to study intermolecular zero-quantum coherences (iZQCs) and double-quantum coherences (iDQCs) in two applications where the three-dimensional structure of the magnetization is important: high-resolution NMR in inhomogeneous fields and contrast enhancement in MRI. Simulations with up to 2 million coupled volume elements (256 x 256 x 32) show that iZQCs can significantly narrow linewidths in the indirectly detected dimension of systems with inhomogeneous fields and explore the effects of shape and orientation of the inhomogeneities. In addition, this study shows that MR images from iZQC and iDQC CRAZED pulse sequences contain fundamentally new contrast, and a modified CRAZED pulse sequence (modCRAZED) can isolate the contrast from chemically inequivalent spins. (C) 2000 Academic Press.