Prenatal mercury exposure and birth weight
Prenatal mercury exposure and birth weight
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DOI：
10.1016/j.reprotox.2018.01.002
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发表时间：
2018-03-01
影响因子：
3.3
通讯作者：
Yokoyama, Kazuhito
中科院分区：
文献类型：
--
作者：
Vigeh, Mohsen;Nishioka, Emiko;Yokoyama, Kazuhito
产前汞暴露对妊娠结果的不利影响仍然是一个公共卫生问题。我们评估了2010年12月至2012年10月期间在日本东京从怀孕早期到分娩的334对母子的产前汞暴露与新生儿人体测量特征之间的关系。孕早期和孕中期血汞水平与出生体重呈负相关（r分别为-0.134和-0.119; p< 0.05）。多元线性回归分析证实了孕早期母体血汞水平与出生体重之间的关系，当调整自变量时（β =-0.170，t= -2.762，p= 0.006）。脐带血中的平均汞含量是母体血液中汞含量的两倍（分别为10.15 +/- 7.74和4.97 +/- 3.25 μ g/L; r = 0.974，p
Adverse effects of prenatal mercury exposure on pregnancy outcomes remain a public health concern. We assessed the relationship between prenatal mercury exposure and newborn anthropometric characteristics in 334 mother-child pairs from the early stages of pregnancy to delivery in Tokyo, apan, between December 2010 and October 2012. We found a negative correlation between blood mercury levels during the first and second trimesters of gestation and birth weight (r = -0.134 and -0.119, respectively; p< 0.05). Multiple linear regression analysis confirmed the relationship between first-trimester maternal blood mercury levels and birth weight when adjusted for independent variables (beta = -0.170, t= -2.762; p= 0.006). Mean mercury levels in umbilical cord blood were twice as high as maternal blood levels (10.15 +/- 7.74 and 4.97 +/- 3.25 mu g/L, respectively; r = 0.974, p