Bisphosphonate therapy for bone loss in patients with osteoporosis and periodontal disease: clinical perspectives and review of the literature.
Bisphosphonate therapy for bone loss in patients with osteoporosis and periodontal disease: clinical perspectives and review of the literature.
复制标题
双磷酸盐治疗骨质疏松症和牙周病患者骨质流失：临床观点和文献综述。
作者：
L. Palomo;N. Bissada;James Liu
随着美国婴儿潮一代的老龄化，越来越多的患者使用双磷酸盐治疗骨质疏松症等全身性骨病。由于双膦酸盐具有抑制骨吸收和破骨细胞活性的能力，因此也可能有益于调节宿主对牙周病治疗的反应。本文献综述探讨了双膦酸盐的作用机制及其在治疗牙周病中的用途。牙科专业人士应继续评估此类药物并密切监测接受双膦酸盐治疗的患者。
As the baby boomer generation in the United States ages, more patients are using bisphosphonates for systemic bone diseases like osteoporosis. Because of their ability to inhibit bone resorption and osteoclastic activity, bisphosphonates may also be beneficial in modulating host response for periodontal disease management. This literature review examines the mechanism of action for bisphosphonates and their uses in treating periodontal disease. The dental profession should continue to evaluate this class of drugs and to closely monitor patients who are on bisphosphonate therapy.