FORMATION OF RIBOSOME-G FACTOR-GDP COMPLEX IN PRESENCE OF FUSIDIC ACID
FORMATION OF RIBOSOME-G FACTOR-GDP COMPLEX IN PRESENCE OF FUSIDIC ACID
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DOI：
10.1016/0006-291x(69)90934-6
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发表时间：
1969-01-01
影响因子：
3.1
通讯作者：
ZIEVE, ST
中科院分区：
文献类型：
--
作者：
BODLEY, JW;ZIEVE, FJ;ZIEVE, ST
当核糖体与G因子和GTP孵育时，形成核糖体-G因子-GDP复合物。夫西地酸并不抑制这种复合物的形成;事实上，在抗生素（10− 3 M）存在的情况下比在没有抗生素的情况下分离出更多的复合物。在存在或不存在抗生素的情况下，检测不到含有GTP的复合物。
When ribosomes are incubated with G factor and GTP, a ribosome-G factor-GDP complex is formed. Fusidic acid does not inhibit the formation of this complex; in fact, more complex is isolated in the presence of the antibiotic (10−3M) than in its absence. No complex containing GTP is detectable in the presence or absence of the antibiotic.