Responsiveness and Construct Validity of a Symptom Scale for Acute Otitis Media
Responsiveness and Construct Validity of a Symptom Scale for Acute Otitis Media
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DOI：
10.1097/inf.0b013e318185a3a0
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发表时间：
2009-01-01
影响因子：
3.6
通讯作者：
Zoffel, Lisa M.
中科院分区：
文献类型：
--
作者：
Shaikh, Nader;Hoberman, Alejandro;Zoffel, Lisa M.
背景资料：由于缓解症状是急性中耳炎（AOM）儿童抗菌治疗的主要目标，因此在研究中测量症状或此类儿童的抗菌有效性非常重要。方法：采用AQM-SOS量表，对3个月~3岁接受抗菌治疗的AOM患儿进行问卷调查。在入组访视时和随访访视（第5 - 7天）时使用该量表，作为每日两次的日志测量。为了评估结构效度，我们在入组时检查了AOM-SOS评分与其他疼痛和功能状态指标评分之间的相关性。为了评估量表的反应性，我们检查了从入组到随访的量表评分变化。我们还研究了规模分数和整体评估的儿童parents.Results之间的协议水平：我们招募了70名儿童（平均年龄12.5个月），其中57返回后续行动。文件AOM-SOS量表评分与其他疼痛和功能状态指标之间的相关性程度范围为0.56至0.84。AOM-SOS的反应性为1.20。结论：AOM-SOS是一种有效的疼痛和功能评定量表。在患病的最初几天内，分数的变化是实质性的，并且通常与父母和临床医生的评估相匹配。AOM-SOS有望作为AOM临床研究的所有结局指标。
Background: Because resolution of symptoms is a primary goal of antimicrobial therapy in children with acute otitis media (AOM), measurement of symptoms in studies or antimicrobial effectiveness in such children is important. We have developed a scale For measuring symptoms of AOM in Young children (AOM-SOS), and we present data oil its construct validity and responsiveness.Methods: We followed children 3 months to 3 years of age with AOM, who were receiving antimicrobial treatment, using file AQM-SOS scale. The scale was administered at the enrollment visit, as a twice-a-day diary measure, and at the follow-up visit (days 5-7). To evaluate construct validity, we examined the correlation, at entry, between AOM-SOS scores and scores oil other measures of pain and functional status. To evaluate the scale's responsiveness, we examined the change in scale scores from entry to follow-up. We also examined the levels of agreement between the scale scores and overall assessments of the children by parents.Results: We enrolled 70 children (mean age 12.5 months') of whom 57 returned for follow-up. The Magnitude of the correlations between file AOM-SOS scale scores and other measures of pain and functional status ranged from 0.56 to 0.84. The responsiveness of the AOM-SOS, as measured by the standardized response mean was 1.20.Conclusions: These data support the validity and responsiveness of the AOM-SOS the scale seems to measure effectively both pain and overall functional status in young children with AOM. Changes in score over the first Few days of illness were substantial and generally matched the assessments both of parents and of clinicians. The AOM-SOS promises to be useful as ail outcome measure in clinical studies of AOM.