Structure of Rad5 provides insights into its role in tolerance to replication stress
Structure of Rad5 provides insights into its role in tolerance to replication stress
复制标题
Rad5 的结构提供了对其在复制压力耐受性中的作用的见解
DOI:
10.1080/23723556.2021.1889348
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发表时间:
2021-03
影响因子:
--
通讯作者:
Song Xiang
中科院分区:
文献类型:
--
作者:
Miaomiao Shen;Nalini Dhingra;Quan Wang;Xiaoxin Gong;Xin Xu;Hengyao Niu;Xiaolan Zhao;Song Xiang
ABSTRACT The Rad5 family of proteins are critical genome maintenance factors, with helicase-like transcription factor (HLTF) and SNF2 histone linker PHD RING helicase (SHRPH) in humans implicated in several types of cancer. How their multiple activities coordinate has been unclear. Our recent study on Rad5 shed light on this question.
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