NEOXALINE, A NEW ALKALOID PRODUCED BY ASPERGILLUS-JAPONICUS PRODUCTION, ISOLATION AND PROPERTIES
NEOXALINE, A NEW ALKALOID PRODUCED BY ASPERGILLUS-JAPONICUS PRODUCTION, ISOLATION AND PROPERTIES
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DOI：
10.7164/antibiotics.32.781
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发表时间：
1979-01-01
影响因子：
3.3
通讯作者：
OMURA, S
中科院分区：
文献类型：
--
作者：
HIRANO, A;IWAI, Y;OMURA, S
本文报道了一种新的生物碱，命名为neoxaline.通过溶剂萃取和硅胶色谱法纯化Fg-551。该化合物不具有抗微生物活性，但对中枢神经系统有微弱的刺激作用。通过元素分析和质谱分析，确定了新恶啉的分子式为C23 H25 N5 O 4。
A new alkaloid named neoxaline was isolated from culture broth of A. japonicus Fg-551 by solvent extraction and silica gel chromatography. The compound does not possess antimicrobial activities, but weakly stimulates the CNS [in mice]. The molecular formula of neoxaline was determined as C23H25N5O4 on the basis of elemental analysis and its mass spectrometry.