Reproducibility and Agreement of Anterior Segment Parameter Measurements Obtained Using the CASIA2 and Spectralis OCT2 Optical Coherence Tomography Devices.
Reproducibility and Agreement of Anterior Segment Parameter Measurements Obtained Using the CASIA2 and Spectralis OCT2 Optical Coherence Tomography Devices.
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DOI：
10.1097/ijg.0000000000000788
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发表时间：
2017-11
影响因子：
2
通讯作者：
Weinreb RN
中科院分区：
文献类型：
--
作者：
Xu BY;Mai DD;Penteado RC;Saunders L;Weinreb RN
旨在评估从Tomey CASIA 2和Heidelberg Spectralis OCT 2眼前节光学相干断层扫描（AS-OCT）设备获得的测量值的再现性和一致性。纳入了10例受试者的20只眼，年龄范围为28 - 45岁，无眼部疾病或眼内手术史。经过一段时间的暗适应后，在标准化暗室环境中使用每种器械进行两次扫描。对每只眼睛和每次扫描沿水平（颞鼻）子午线的一幅AS-OCT图像进行沿着分析。使用计算机提供的图像分析程序测量透镜穹窿（LV）、瞳孔直径（PD）、前房宽度（ACW）、房角开放距离（AOD）、虹膜小梁间隙面积（TISA）和巩膜棘角（SSAngle）。计算类内相关性（ICC）值、变异系数和Bland-Altman图，以评估测量值的器械内相关性和器械间一致性。对于CASIA（ICC范围0.86至0.99）和Spectralis（ICC范围0.79至1.00），测量值的器械内重现性极佳。除ACW（ICC 0.20）外，所有参数的测量值（ICC范围为0.78至0.93）也具有良好的器械间相关性。线性回归模型和Bland-Altman图显示，当测量值较小时，这种关系最强。CASIA 2和Spectralis OCT 2的眼前节参数测量值具有出色的器械内重现性和良好的器械间一致性。但是，每种器械获得的测量值不应视为可互换。
To assess the reproducibility and agreement of measurement values obtained from the Tomey CASIA2 and Heidelberg Spectralis OCT2 anterior segment optical coherence tomography (AS-OCT) devices. Twenty eyes from ten subjects ranging from age 28 to 45 years with no history of eye conditions or intraocular surgery were included. Two scans were obtained with each device in a standardized dark-room environment after a period of dark adaptation. One AS-OCT image along the horizontal (temporal-nasal) meridian was analyzed per eye and per scan. Lens vault (LV), pupil diameter (PD), anterior chamber width (ACW), angle opening distance (AOD), trabecular iris space area (TISA), and scleral spur angle (SSAngle) were measured using manufacturer-provided image analysis programs. Intra-class correlation (ICC) values, coefficients of variation, and Bland-Altman plots were computed to assess the intra-device correlation and inter-device agreement of measurement values. There was excellent intra-device reproducibility of measurement values for both the CASIA (ICC range 0.86 to 0.99) and Spectralis (ICC range 0.79 to 1.00). There was also excellent inter-device correlation of measurement values (ICC range 0.78 to 0.93) for all parameters except ACW (ICC 0.20). Linear regression models and Bland-Altman plots showed that this relationship was strongest when measurement values were small. There is excellent intra-device reproducibility and good inter-device agreement of anterior segment parameter measurement values for the CASIA2 and Spectralis OCT2. However, the measurements obtained with each device should not be considered interchangeable.