Quantification of the skin sparing effect achievable with high-energy photon beams when carbon fiber tables are used
Quantification of the skin sparing effect achievable with high-energy photon beams when carbon fiber tables are used
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DOI：
10.1016/j.radonc.2009.05.008
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发表时间：
2009-10-01
影响因子：
5.7
通讯作者：
Moros, Eduardo G.
中科院分区：
文献类型：
--
作者：
Mihaylov, Ivaylo B.;Penagaricano, Jose;Moros, Eduardo G.
目的：为了量化皮肤剂量的使用碳纤维沙发（CFC）patientsupport.Materials和方法：BrainLab的CFC进行了评估，为五个前列腺患者和五个肺部患者。对于每名患者PTV，器官风险（OAR），和0.3厘米厚的皮肤轮廓上的病人的后表面进行了概述。每个患者生成两组IMRT计划，每组由4、5、7和9个射束组成。除了在第一组中仅使用6 MV能量，而在第二组（混合能量）中穿过CFC的光束的光子能量为18 MV之外，这些组是相同的。对每例患者的计划进行标准化，以将相同剂量输送至PTV的95%。CFC皮肤剂量通过皮肤体积的1%（D（1%））接收的最大剂量来评估。结果：混合能量计划的D（1%）随着计划中射束数从9个减少到4个而从18%增加到23%以上。结论：即使在9射束混合能量计划中，皮肤剂量也高达处方剂量的70%。因此，混合能量计划可能对接受更高分次剂量治疗的患者更有益。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。放射治疗和肿瘤学93（2009）147-152
Purpose: To quantify the skin doses resulting from the use of carbon fiber couches (CFCs) for patient support.Materials and methods: BrainLab's CFC was evaluated for five prostate patients and five lung patients. For each patient PTV, organs at risk (OARs), and a 0.3 cm thick skin contour on the patient's posterior surface were outlined. Two sets of IMRT plans, each consisting of 4, 5, 7, and 9 beams, were generated per patient. The sets were identical with the exception that in the first set only 6 MV energy was used, while in the second set (mixed energy) the photon energy of the beams traversing the CFC was 18 MV. The plans for each patient were normalized to deliver the same dose to 95% of the PTV. The CFC skin dose was evaluated by the maximum dose received by 1% (D(1%)) of the skin Volume. Paired one-tailed t-tests were used to establish the statistical significance.Results: The mixed energy plans resulted in D(1%) increase from 18% to more than 23% as the number of beams in the plan was decreased from 9 to 4.Conclusions: Skin doses as high as similar to 70% of the prescription dose were found even in 9-beam mixed energy plans. Therefore mixed energy plans may be more beneficial for patients treated with higher fractional doses. (C) 2009 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 93 (2009) 147-152