Investigation of Helicobacter pylori in bronchoscopic lung specimens of young male patients with bronchiectasis but without gastrointestinal symptoms

Investigation of Helicobacter pylori in bronchoscopic lung specimens of young male patients with bronchiectasis but without gastrointestinal symptoms
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DOI:
10.1111/j.1198-743x.2004.00868.x
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发表时间:
2004-03-01
影响因子:
14.2
通讯作者:
Kunter, E
Kunter, E
中科院分区:
医学1区
文献类型:
--
作者:
Ilvan, A;Ozturkeri, H;Kunter, E

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检测了 31 名无胃肠道症状的年轻男性支气管扩张患者和 56 名健康男性的血清抗幽门螺杆菌 IgG 水平。还通过对受保护的导管刷和支气管扩张部位的活检标本进行快速尿素酶测试、培养和组织病理学检查来调查幽门螺杆菌的可能存在。在支气管扩张患者组中未发现幽门螺杆菌感染的血清学、微生物学或组织学证据。幽门螺杆菌似乎不是支气管扩张症中的感染因子或慢性定植物,并且可能在该疾病的进展中没有显着作用。
Anti-Helicobacter pylori IgG serum levels were measured in 31 young male bronchiectasis patients without gastrointestinal symptoms, and 56 healthy males. The possible presence of H. pylori was also investigated by rapid urease tests, culture and histopathological examination of protected catheter brush and biopsy specimens from the bronchiectatic site. No serological, microbiological or histological evidence of H. pylori infection was found in the bronchiectasis patient group. H. pylori did not appear to be an agent of infection or chronic colonisation in bronchiectasis, and may not have a significant role in the progression of this disease.