ESTRO ACROP consensus guideline on CT- and MRI-based target volume delineation for primary radiation therapy of localized prostate cancer
ESTRO ACROP consensus guideline on CT- and MRI-based target volume delineation for primary radiation therapy of localized prostate cancer
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DOI：
10.1016/j.radonc.2018.01.014
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发表时间：
2018-04-01
影响因子：
5.7
通讯作者：
Fonteyne, Valerie
中科院分区：
文献类型：
--
作者：
Salembier, Carl;Villeirs, Geert;Fonteyne, Valerie
背景和目的：临床靶体积（CTVs）的描绘仍然是放射治疗（RT）中的薄弱环节，并且观察者之间存在很大的差异。在原发性前列腺癌中，靶点和危险器官划分的指南很少。其目的是制定一个划定指南之间达成共识的广泛的欧洲组的放射肿瘤学家。材料和方法：一个ESTRO轮廓共识小组组成的领先的放射肿瘤学家和一个放射科医生与已知的专业知识在前列腺癌被要求划定共同注册的CT和MRI扫描的前列腺，精囊和直肠。在对不同轮廓进行评估、文献回顾和通过电子邮件进行多次非正式讨论后，定义了CTV定义，并制定了前列腺和直肠CTV轮廓的指南。结果：小组达成了共识，CTV轮廓定义可用作局限性前列腺癌的原发性RT指南。ESTRO共识CT/MRI为基础的CTV划定的局限性前列腺癌的主要RT，由广泛的基础的放射肿瘤学社区的认可，提出提高一致性和可靠性。(C)2018 Elsevier B. V.版权所有。
Background and purpose: Delineation of clinical target volumes (CTVs) remains a weak link in radiation therapy (RT), and large inter-observer variation is seen. Guidelines for target and organs at risk delineation for prostate cancer in the primary setting are scarce. The aim was to develop a delineation guideline obtained by consensus between a broad European group of radiation oncologists.Material and methods: An ESTRO contouring consensus panel consisting of leading radiation oncologists and one radiologist with known subspecialty expertise in prostate cancer was asked to delineate the prostate, seminal vesicles and rectum on co-registered CT and MRI scans. After evaluation of the different contours, literature review and multiple informal discussions by electronic mail a CTV definition was defined and a guide for contouring the CTV of the prostate and the rectum was developed.Results: The panel achieved consensus CTV contouring definitions to be used as guideline for primary RT of localized prostate cancer.Conclusion: The ESTRO consensus on CT/MRI based CTV delineation for primary RT of localized prostate cancer, endorsed by a broad base of the radiation oncology community, is presented to improve consistency and reliability. (C) 2018 Elsevier B.V. All rights reserved.