Abdominal bloating in employed adults: Prevalence, risk factors, and association with other bowel disorders
Abdominal bloating in employed adults: Prevalence, risk factors, and association with other bowel disorders
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DOI：
10.1111/j.1572-0241.2007.01755.x
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发表时间：
2008-05-01
影响因子：
9.8
通讯作者：
Hickam, David H.
中科院分区：
文献类型：
--
作者：
Tuteja, Ashok K.;Talley, Nicholas J.;Hickam, David H.
背景腹胀很常见，但其作为潜在疾病标志的重要性尚未定义。目的：我们报道腹胀的危险因素，它与体力活动和生活质量(QOL)的关系，以及它对功能性肠道疾病的预测价值。方法：这是一项基于人口的横断面研究，涉及退伍军人事务部黑山医疗保健系统的1,069名员工。有效的肠道疾病问卷被用来确定患有腹胀和其他肠道疾病的受试者。使用SF36(简式36)问卷评估腹胀与生活质量的关系。结果：有效率为72%(1069人中有723人)。21%的受试者有腹胀症状(95%可信区间为17.7-23.7)，有肠易激综合征，35%有非肠易激综合征便秘，23%有非肠易激综合征腹泻，42%有消化不良。7%的受试者报告了功能性腹胀(即在没有其他肠道疾病的情况下出现腹胀)(95%可信区间5.2-9.0)。在腹胀的患者中，28%的人患有IBS，25%的人患有非IBS便秘，8%的人患有非IBS腹泻，30%的人患有消化不良。腹胀对功能性肠病诊断的阳性预测值为66%，阴性预测值为87%。唯一的危险因素是吸烟和大剂量阿司匹林。腹胀与体力活动无关。有腹胀的受试者在SF36的所有子量表上的生活质量都低于无腹胀的受试者。结论：腹胀是其他健康成年人的常见症状，通常与功能性肠病有关，但不是预测。吸烟和服用大剂量阿司匹林与腹胀有关，而体力活动与此无关。
BACKGROUND Bloating is common, but its significance as a marker of underlying disease has not been defined.AND AIMS: We report on risk factors for bloating, its relationship to physical activity and quality of life (QOL), and its predictive value for functional bowel disorders.METHODS: This is a cross-sectional population-based study of 1,069 employees of the Veterans Affairs Black Hills Health Care System. The validated Bowel Disease Questionnaire was used to identify subjects with abdominal bloating and other bowel disorders. The association of bloating with QOL was assessed using the SF36 (Short-Form 36) questionnaire. Physical activity was assessed using the modified Baecke questionnaire.RESULTS: The response rate was 72% (723 of 1,069). Bloating was reported by 21% of all subjects (95% confidence interval [CI] 17.7-23.7), 64% with irritable bowel syndrome (IBS), 35% with non-IBS constipation, 23% with non-IBS diarrhea, and 42% with dyspepsia. Functional bloating (i.e., bloating in the absence of other bowel disorders) was reported by 7% of subjects (95% CI 5.2-9.0). Of those with bloating, 28% had IBS, 25% non-IBS constipation, 8% non-IBS diarrhea, and 30% dyspepsia. The positive and negative predictive values of bloating in the diagnosis of functional bowel disorder were 66% and 87%, respectively. The only risk factors were smoking and high-dose aspirin. Bloating was not associated with physical activity. QOL on all subscales of SF36 was lower in subjects with bloating than those without bloating.CONCLUSIONS: Bloating is a common symptom in otherwise healthy adults, and is often associated with but not predictive of functional bowel disorders. Smoking and high-dose aspirin are associated with bloating while physical activity is not.