miR-3664-5P suppresses the proliferation and metastasis of gastric cancer by attenuating the NF-B signaling pathway through targeting MTDH

miR-3664-5P suppresses the proliferation and metastasis of gastric cancer by attenuating the NF-B signaling pathway through targeting MTDH
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DOI:
10.3892/ijo.2019.4680
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发表时间:
2019-03-01
影响因子:
5.2
通讯作者:
Tang, Liming
Tang, Liming
中科院分区:
医学2区
文献类型:
--
作者:
Jiao, Yuwen;Yang, Haojun;Tang, Liming

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胃癌是世界范围内最常见和最致命的癌症之一,其具体机制尚未完全阐明。microRNA (miR)-3664-5P很少被研究,本研究的目的是评估miR-3664-5P与GC之间的关系。采用逆转录-定量聚合酶链反应法检测miR-3664-5P在100 GC(0.1846 +/- 0.08276)和配对正常组织(0.4382 +/- 0.1595)中的表达差异(P
Gastric cancer (GC) is one of the most common and fatal types of cancers worldwide and the specific mechanism has not been completely elucidated. microRNA (miR)-3664-5P has rarely been studied and the aim of the present study was to assess an association between miR-3664-5P and GC. Differences in miR-3664-5P expression in 100 GC (0.1846 +/- 0.08276) and paired normal tissues (0.4382 +/- 0.1595) were detected using reverse transcription-quantitative polymerase chain reaction assays (P