A PROSPECTIVE MICROBIOLOGIC STUDY OF BACTERIURIA IN PATIENTS WITH CHRONIC INDWELLING URETHRAL CATHETERS
A PROSPECTIVE MICROBIOLOGIC STUDY OF BACTERIURIA IN PATIENTS WITH CHRONIC INDWELLING URETHRAL CATHETERS
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DOI：
10.1093/infdis/146.6.719
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发表时间：
1982-01-01
影响因子：
6.4
通讯作者：
ANTHONY, WC
中科院分区：
文献类型：
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作者：
WARREN, JW;TENNEY, JH;ANTHONY, WC
细菌尿在长期导尿患者中很常见，并与急性和慢性并发症有关。在20例长期导尿患者连续605周尿液样本中，98%含有高浓度细菌，77%为多微生物。新发菌尿的平均间隔时间为1.8周。大多数种类的细菌引起5-7次新的细菌尿/100周的导尿。尽管进入导管腔的途径是相似的，但细菌发作的持续时间因物种而异。非肠球菌性革兰氏阳性球菌引起的菌尿发作中，75%持续时间< 1周。大肠杆菌、奇异变形杆菌和铜绿假单胞菌引起的细菌尿发作的平均持续时间为4-6周；由天意菌引起的疾病平均为10周，最长可达36周。因此，细菌尿的发病率非常高，几乎达到100%，这是由于许多不同种类的细菌引起的高发病率，加上一些革兰氏阴性杆菌在导管和尿路中的长期驻留。
Bacteriuria is common in chronically catheterized patients and is associated with both acute and chronic complications. Of 605 consecutive weekly urine specimens from 20 chronically catheterized patients, 98% contained bacteria at high concentrations and 77% were polymicrobial. The mean interval between new episodes of bacteriuria was 1.8 wk. Most species of bacteria caused 5-7 new episodes of bacteriuria/100 wk of catheterization. Even though access to the catheter lumen was similar, the duration of bacteriuric episodes varied greatly by species. Of the episodes of bacteriuria caused by nonenterococcal gram-positive cocci, > 75% lasted < 1 wk. Mean durations of episodes of bacteriuria due to Escherichia coli, Proteus mirabilis and Pseudomonas aeruginosa were 4-6 wk; those due to Providencia stuartii averaged 10 wk and ranged up to 36 wk. Thus, the very high prevalence of bacteriuria, virtually 100%, was a result of a high incidence caused by many different species, combined with the prolonged residence of some gram-negative bacilli in the catheter and urinary tract.