LEAD IN HUMAN BONES - INVESTIGATIONS ON AN OCCUPATIONALLY NON-EXPOSED POPULATION IN SOUTHERN BAVARIA (FRG) .1. ADULTS
LEAD IN HUMAN BONES - INVESTIGATIONS ON AN OCCUPATIONALLY NON-EXPOSED POPULATION IN SOUTHERN BAVARIA (FRG) .1. ADULTS
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DOI：
10.1016/0048-9697(87)90252-x
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发表时间：
1987-07-01
影响因子：
9.8
通讯作者：
BAUR, C
中科院分区：
文献类型：
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作者：
DRASCH, GA;BOHM, J;BAUR, C
本文用原子吸收分光光度法测定了1983年10月至1985年2月间死亡的240名非职业性接触铅的成年人的三种不同骨骼（骨盆骨、股骨中部皮质骨和颞骨岩部）中铅的浓度。就性别、年龄和居住地（城市和农村）而言，实现了均衡分布（每10岁有10名城市女性、10名农村女性、10名城市男性和10名农村男性）。以皮质骨为主的股骨（几何平均值，3.86 mg Pb/kg骨湿重）颞骨（5.59）的铅浓度高于骨小梁（1.65）（每例n = 240）。对于三种类型的骨骼中的每一种，男性（n = 120）的平均铅含量显著高于女性（n = 120）;例如，骨盆骨的平均铅含量为38.3%，股骨中段的平均铅含量为51.3%，颞骨的平均铅含量为24.8%。当比较慕尼黑的居民（人口> 1 × 10 - 4）时，没有获得统计学显著差异。106)（n = 120）与巴伐利亚南部其余地区的人（n = 120）。颞骨铅含量随年龄增长而逐渐增加。相比之下，在股骨中段和盆骨的铅含量达到一个平台，在中年减少在较高的年龄，这种下降是更明显的女性。平均电极导线体负荷计算为41.4 ±。24.2所有雄性（n = 120）和24.1 . ±. 12.5所有雌性（n = 120）。我们的结论是，铅的负担，至少在该地区的调查，在过去的十年中已经减少，可能是因为减少了汽油中的铅含量。
The concentration of lead in three different bones (pelvic bone, cortical part of the mid-femur, petrous portion of the temporal bone) of 240 occupationally non-exposed adults who died between October 1983 and February 1985 was determined by electrothermal atomic absorption spectrometry. As far as sex, age and domicile (urban and rural) are concerned, a balanced distribution was achieved (for each age decade 10 urban females, 10 rural females, 10 urban males and 10 rural males). The predominantly cortical femur (geom. mean, 3.86 mg Pb/kg bone wet wt.) and temporal bones (5.59) showed higher Pb concentrations than the trabecular pelvic bone (1.65) (in each case n = 240). For each of the three types of bone, the mean lead content of the males (n = 120) was significantly higher than those of the females (n = 120); e.g. for pelvic bone by 38.3%, mid-femur by 51.3% and temporal bone by 24.8%. No statistically significant difference was obtained when comparing residents of Munich (population > 1 .times. 106) (n = 120) with people in the remaining parts of Southern Bavaria (n = 120). The Pb content of the temporal bone increased steadily with age. In contrast, in the mid-femur and the pelvic bone the Pb content reaches a plateau in middle age with a decrease at higher ages; this decline is more distinct for females. The mean lead body burden was calculated to be 41.4 .+-. 24.2 mg for all males (n = 120) and 24.1 .+-. 12.5 mg for all females (n = 120). We conclude that the lead burden, at least in the area investigated, has been reduced in the last decade, probably because of a reduction in the lead content of petrol.