Necrolytic migratory erythema and zinc deficiency
Necrolytic migratory erythema and zinc deficiency
复制标题
坏死性游走性红斑和缺锌
DOI：
10.1046/j.1365-2133.1997.6761623.x
复制
发表时间：
1997
影响因子：
10.3
通讯作者：
N. Reynolds
中科院分区：
文献类型：
--
作者：
S. Sinclair;N. Reynolds
坏死溶解性游走性红斑（NME）是一种罕见的疾病，通常与循环胰高血糖素和胰高血糖素瘤的高血浆水平相关。我们报告一位肝硬化病人，其临床及组织学表现为非代谢性脑膜炎。研究显示胰高血糖素水平正常，无胰高血糖素瘤证据。血清锌水平低于正常范围，补锌可使皮疹迅速完全消退。
Necrolytic migratory erythema (NME) is an uncommon condition classically associated with high plasma levels of circulating glucagon and a glucagonoma. We report a patient with cirrhosis who showed clinical and histological features of NME. Investigation revealed normal glucagon levels without evidence of glucagonoma. Serum zinc levels were below the normal range and zinc supplementation resulted in rapid and complete resolution of the eruption.