Cardiac patients who completed a longitudinal psychosocial study had a different clinical and psychosocial baseline profile than patients who dropped out prematurely

Cardiac patients who completed a longitudinal psychosocial study had a different clinical and psychosocial baseline profile than patients who dropped out prematurely
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DOI:
10.1177/2047487313506548
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发表时间:
2015-02-01
影响因子:
8.3
通讯作者:
Boersma, Eric
Boersma, Eric
中科院分区:
医学1区
文献类型:
--
作者:
Damen, Nikki L.;Versteeg, Henneke;Boersma, Eric

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无反应是对纵向社会心理研究外部有效性的严重威胁。完成心理社会研究的冠状动脉疾病患者与因无反应而过早退出研究的冠状动脉疾病患者之间的潜在系统差异知之甚少,或者退出研究是否可能具有不同的心血管风险。我们研究了1132例连续接受经皮冠状动脉介入治疗(PCI)的患者。在基线时,所有患者完成医院焦虑和抑郁量表(HADS)和D型量表(DS14)。在12个月的随访中,70.8% (n=802)的患者完成了两份问卷,29.2% (n=330)的患者退出。我们观察到完成者和辍学者在社会人口学、临床和心理基线特征方面存在显著差异。与完全戒烟者相比,戒烟者更年轻,吸烟的可能性更大,但服用心血管药物(包括钙拮抗剂和血管紧张素转换酶抑制剂)的频率更低。与完成者相比,辍学者更常出现抑郁、焦虑和消极情绪(均p值)
Non-response is a serious threat to the external validity of longitudinal psychosocial studies. Little is known about potential systematic differences between patients with coronary artery disease who complete a psychosocial study and those who drop out prematurely due to non-response, or whether drop-outs may have a different cardiovascular risk. We studied a cohort of 1132 consecutive patients undergoing percutaneous coronary intervention (PCI). At baseline, all patients completed the Hospital Anxiety and Depression Scale (HADS) and the Type D Scale (DS14). At 12 months follow-up, 70.8% (n=802) of patients completed both questionnaires, while 29.2% (n=330) dropped out. We observed significant differences in socio-demographic, clinical, and psychological baseline characteristics between completers and drop-outs. Drop-outs were younger, more likely to smoke, but less often prescribed cardiovascular medications, including calcium antagonists and angiotensin-converting enzyme inhibitors, as compared with completers. Drop-outs more often had depression, anxiety, and negative affectivity, as compared with completers (all p-values