Electronic cleansing in computed tomography colonography using AT layer identification with integration of gradient directional second derivative and material fraction model.

Electronic cleansing in computed tomography colonography using AT layer identification with integration of gradient directional second derivative and material fraction model.
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DOI:
10.1186/s12880-017-0224-6
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发表时间:
2017-09-04
影响因子:
2.7
通讯作者:
Lipikorn R
Lipikorn R
中科院分区:
医学4区
文献类型:
--
作者:
Chunhapongpipat K;Boonklurb R;Chaopathomkul B;Sirisup S;Lipikorn R

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在计算机断层扫描结肠成像图像中,应用电子清洁(EC)以去除不透明的残留物质,称为粪便标记物质(FTM),使用阳性造影剂标记剂和泻药以促进息肉检测。提出的EC,EC道具,将梯度方向二阶导数集成到材料分数模型中,以在FTM下保留浸没的软组织(ST)。三种材料分数模型用于去除空气标记(AT)层和T型接头处的FTM和伪影,其中空气、ST和FTM材料同时相遇。此外,所提出的AT层识别用于区分AT层与空气组织标记(ATT)层,以便在清洁期间保留ATT层。由腹部放射科医师对467张三维带视图图像进行了临床评价,采用4个清洁质量等级,并提出了5种低质量EC的原因。根据EC prop的结果近似计算T型连接处剩余伪影的数量。根据放射科医生的偏好,通过Client 3.0软件EC syngo和快速三材料建模EC prev将EC prop的结果与syngo的结果进行比较。双尾配对Wilcoxon符号秩检验用于指示统计学显著性。清洁质素的平均评分为2.89分(满分4分)。86.94%的测试图像中的T形连接处的伪影可以被去除,而仅13.06%的测试图像中的T形连接处的伪影不能被去除。对于13.06%的测试图像,EC prop的结果比EC syngo的结果更好(p<0.008)。对于所有测试图像,EC prop的结果比EC prev的结果更优选(p<0.001)。最后,视觉评估表明,EC prop可以保留ATT层,淹没息肉和褶皱,而EC prev只能保留淹没褶皱,但不能保留ATT层。从我们的实现中,EC prop可以提高现有EC的性能,使得它可以保留ST,特别是ATT层,并去除之前从未被任何其他方法提出过的T型接头处的伪影。
In computed tomography colonography images, electronic cleansing (EC) is applied to remove opacified residual materials, called fecal-tagging materials (FTM), using positive-contrast tagging agents and laxative to facilitate polyp detection. The proposed EC, EC prop, integrates the gradient directional second derivative into material fraction model to preserve submerged soft tissue (ST) under FTM. Three-material fraction model is used to remove FTM and artifacts at air-tagging (AT) layers and T-junctions where air, ST, and FTM material meet simultaneously. Moreover, the proposed AT layer identification is used to distinguish AT layers from air-tissue-tagging (ATT) layers in order to preserve ATT layers during cleansing. The clinical evaluation on 467 3-Dimensional band view images was conducted by the abdominal radiologist using four grading levels of cleansing quality with five causes of low quality EC. The amount of the remaining artifacts at T-junctions was approximated from the results of EC prop. The results from EC prop were compared with the results from syngo.via Client 3.0 Software, EC syngo, and the fast three-material modeling, EC prev, using the preference of the radiologist. Two-tailed paired Wilcoxon signed rank test is used to indicate statistical significance. The average grade on cleansing quality is 2.89 out of 4. The artifacts at T-junctions from 86.94% of the test images can be removed, whereas artifacts at T-junctions from only 13.06% of the test images cannot be removed. For 13.06% of the test images, the results from EC prop are more preferable to the results from EC syngo (p<0.008). For all the test images, the results from EC prop are more preferable to the results from EC prev (p<0.001). Finally, the visual assessment shows that EC prop can preserve ATT layers, submerged polyps and folds while EC prev can preserve only submerged folds but fails to preserve ATT layers. From our implementation, EC prop can improve the performance of the existing EC, such that it can preserve ST, especially ATT layers and remove the artifacts at T-junctions which have never been proposed by any other methods before.
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