FUNCTIONALIZATION OF POLY(L-LACTIDE) MACROMONOMERS BY RING-OPENING POLYMERIZATION OF L-LACTIDE INITIATED WITH HYDROXYETHYL METHACRYLATE ALUMINUM ALKOXIDES
FUNCTIONALIZATION OF POLY(L-LACTIDE) MACROMONOMERS BY RING-OPENING POLYMERIZATION OF L-LACTIDE INITIATED WITH HYDROXYETHYL METHACRYLATE ALUMINUM ALKOXIDES
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DOI：
10.1016/0032-3861(95)90689-y
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发表时间：
1995-01-01
期刊：
影响因子：
4.6
通讯作者：
SANROMAN, J
中科院分区：
文献类型：
--
作者：
EGUIBURU, JL;BERRIDI, MJF;SANROMAN, J
以甲基丙烯酸单羟乙酯和三羟乙酯-醇铝为引发剂，通过L-丙交酯（LA）的开环聚合，合成了末端官能化的甲基丙烯酸羟乙酯-聚乳酸（HEMA-PLA）大分子单体。在甲苯中在高真空和60 ℃下进行的聚合呈现活性特征，导致形成线性聚合物而没有环化副反应。在用稀HCl水解活性生长中心后，在聚合物链的末端形成一个羟基。为了研究端基的结构特征，通过在低的[LA]/[AI]比率下使用单-和三-HEMA-铝醇盐获得相对低分子量的大分子单体。通过傅里叶变换红外和H-1核磁共振光谱分析得到的聚合物，同时考虑到低分子量模型化合物，甲基丙烯酸2-乙酰氧基乙酯，它再现了PLA大分子单体的HEMA官能端基的结构的信号。
End-functionalized hydroxyethyl methacrylate macromonomers of poly(L-lactide) (HEMA-PLA) were synthesized by the ring-opening polymerization of L-lactide (LA), using mono- and trihydroxyethyl methacrylate-aluminium alkoxides as initiators. The polymerization carried out in toluene at high vacuum and 60 degrees C presented a living character, giving rise to the formation of a linear polymer without cyclization side reactions. After hydrolysis of the active growing centres with dilute HCl, one hydroxyl group was formed at the end of the polymeric chains. To study the structural characteristics of the end-groups, macromonomers of relatively low molecular weight were obtained by using the mono- and tri-HEMA-aluminium alkoxides at a low ratio of [LA]/[AI]. The polymers obtained were analysed by Fourier-transform infra-red and H-1 nuclear magnetic resonance spectroscopies, taking into consideration the signals of a low-molecular-weight model compound, 2-acetyloxyethyl methacrylate, which reproduces the structure of the HEMA functional end-group of the PLA macromonomer.