High Prevalence of Pancreatic Cysts Detected by Screening Magnetic Resonance Imaging Examinations
High Prevalence of Pancreatic Cysts Detected by Screening Magnetic Resonance Imaging Examinations
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DOI：
10.1016/j.cgh.2010.05.017
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发表时间：
2010-09-01
影响因子：
12.6
通讯作者：
Bruno, Marco J.
中科院分区：
文献类型：
--
作者：
de Jong, Koen;Nio, C. Yung;Bruno, Marco J.
背景与目的：胰腺囊肿的患病率尚不清楚，但无症状胰腺囊肿的诊断率越来越高。我们调查了作为预防性体检的一部分，通过磁共振成像（MRI）筛查的个体中胰腺囊肿的患病率。方法：在预防性医疗保健研究所接受腹部MRI的连续人员（n = 2803; 1821名男性;平均年龄51.1 ± 10.8岁）的数据来自前瞻性数据库。所有人都填写了一份申请表，包括有关可能的腹部投诉和先前手术的问题。对MRI报告进行了审查，以确定是否存在胰腺囊肿。所有阳性MRI报告的原始图像集和阴性系列的代表性样本由设盲的独立放射科医生重新评估。结果：66人报告胰腺囊肿（2.4%; 95%可信区间，1.9-3.0）;患病率与年龄增长相关（P <0.001）。性别之间的患病率没有差异（P = .769）。腹部不适和胰腺囊肿的存在之间没有相关性（P = 0.542）。4个囊肿（6%）大于2cm，3个囊肿（5%）大于3cm。由独立放射科医师审查原始图像集未显著改变这些结果。结论：在一个大的连续系列的个人谁接受了MRI在预防性体检胰腺囊肿的患病率为2.4%。患病率随着年龄的增长而增加，但在性别之间没有差异。只有少数囊肿大于2 cm。
BACKGROUND & AIMS: The prevalence of pancreatic cysts is not known, but asymptomatic pancreatic cysts are diagnosed with increasing frequency. We investigated the prevalence of pancreatic cysts in individuals who were screened by magnetic resonance imaging (MRI) as part of a preventive medical examination. METHODS: Data from consecutive persons who underwent abdominal MRI (n = 2803; 1821 men; mean age, 51.1 +/- 10.8 y) at an institute of preventive medical care were included from a prospective database. All individuals had completed an application form including questions about possible abdominal complaints and prior surgery. MRI reports were reviewed for the presence of pancreatic cysts. Original image sets of all positive MRI reports and a representative sample of the negative series were re-assessed by a blinded, independent radiologist. RESULTS: Pancreatic cysts were reported in 66 persons (2.4%; 95% confidence interval, 1.9-3.0); prevalence correlated with increasing age (P < .001). There was no difference in prevalence between sexes (P = .769). There was no correlation between abdominal complaints and the presence of pancreatic cysts (P = .542). Four cysts (6%) were larger than 2 cm and 3 (5%) were larger than 3 cm. Review of the original image sets by the independent radiologist did not significantly change these findings. CONCLUSIONS: The prevalence of pancreatic cysts in a large consecutive series of individuals who underwent an MRI at a preventive medical examination was 2.4%. Prevalence increased with age, but did not differ between sexes. Only a minority of cysts were larger than 2 cm.