Sex-Based Differences in Presentation, Treatment, and Complications Among Older Adults Hospitalized for Acute Myocardial Infarction The SILVER-AMI Study
Sex-Based Differences in Presentation, Treatment, and Complications Among Older Adults Hospitalized for Acute Myocardial Infarction The SILVER-AMI Study
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因急性心肌梗死住院的老年人在症状表现、治疗及并发症方面的性别差异——SILVER - AMI研究
DOI：
10.1161/circoutcomes.119.005691
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发表时间：
2019-10-01
影响因子：
6.9
通讯作者：
Dodson, John A.
中科院分区：
文献类型：
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作者：
Nanna, Michael G.;Hajduk, Alexandra M.;Dodson, John A.
背景：关于老年急性心肌梗死（AMI）患者性别差异的研究结果喜忧参半。因此，我们试图评估大量特征良好的老年人（>= 75岁）因AMI住院的性别差异，包括表现特征、治疗、功能障碍和住院并发症。方法和结果：我们分析了参加SILVER-AMI（老年急性心肌梗死患者危险因素的综合评价）的参与者的数据，这是一项前瞻性观察性研究，包括3041例因AMI住院的老年患者（44%为女性）。参与者按AMI亚型（ST段抬高型心肌梗死[STEMI]和非STEMI [NSTEMI]）分层，随后评估临床表现、功能障碍、管理和院内并发症的性别差异。在研究样本中，女性略大于男性（NSTEMI：82.1 vs 81.3，P
Background: Studies of sex-based differences in older adults with acute myocardial infarction (AMI) have yielded mixed results. We, therefore, sought to evaluate sex-based differences in presentation characteristics, treatments, functional impairments, and in-hospital complications in a large, well-characterized population of older adults (>= 75 years) hospitalized with AMI. Methods and Results: We analyzed data from participants enrolled in SILVER-AMI (Comprehensive Evaluation of Risk Factors in Older Patients With Acute Myocardial Infarction)-a prospective observational study consisting of 3041 older patients (44% women) hospitalized for AMI. Participants were stratified by AMI subtype (ST-segment-elevation myocardial infarction [STEMI] and non-STEMI [NSTEMI]) and subsequently evaluated for sex-based differences in clinical presentation, functional impairments, management, and in-hospital complications. Among the study sample, women were slightly older than men (NSTEMI: 82.1 versus 81.3, P