ANTIGENICITY OF COLLAGEN AND ITS APPLICATION IN SEROLOGICAL INVESTIGATION OF RHEUMATOID ARTHRITIS SERA
ANTIGENICITY OF COLLAGEN AND ITS APPLICATION IN SEROLOGICAL INVESTIGATION OF RHEUMATOID ARTHRITIS SERA
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DOI：
10.1159/000229376
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发表时间：
1963-01-01
期刊：
影响因子：
--
通讯作者：
TIMPL, R
中科院分区：
文献类型：
--
作者：
STEFFEN, C;TIMPL, R
描述了从胶原蛋白制备异羟肟胶原蛋白的方法。其分子量约为20,000，可溶于水介质。它对兔子有抗原性。描述了此类血清与其他胶原制剂的交叉反应。没有物种特异性。在许多类风湿性关节炎病例的血清中都发现了这种抗体。
The preparation of hydroxam-collagen from collagen is described. It has a molecular weight of about 20,000 and is soluble in aqueous media. It is antigenic in rabbits. Cross-reactions of such sera with other collagen preparations are described. There is no species specificity. Antibodies of this kind are found in the sera of many cases of rheumatoid arthritis.