Time of closure of ductus venosus in term and preterm neonates
Time of closure of ductus venosus in term and preterm neonates
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DOI：
10.1136/fn.85.1.f57
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发表时间：
2001-07-01
影响因子：
4.4
通讯作者：
Onishi, S
中科院分区：
文献类型：
--
作者：
Kondo, M;Itoh, S;Onishi, S
目的：探讨胎龄、出生体重、产前皮质类固醇给药与静脉导管关闭时间的关系。方法：对98例30 ~ 41周胎龄新生儿进行静脉导管闭合前每日超声检查。结果：30-33周胎龄新生儿静脉导管关闭时间为6.0（2.4）天（平均（SD））；在34-36周的孕龄中，它在6.1（2.8）天关闭；而在37-41周孕龄的孕妇中，妊娠期为4.2（2.1）天。在30-34周胎龄的新生儿中，还研究了产前给药皮质类固醇对闭合时间的影响。皮质类固醇组闭合时间为5.5（2.4）天，其余组为7.5（2.1）天。结论：大胎龄或高出生体重的新生儿，静脉导管在出生后较早关闭。产前皮质类固醇管理有显著的效果，促进关闭。
Aim-To investigate the relation between gestational age, birth weight, and antenatal corticosteroid administration and the time of ductus venosus closure.Methods-Ninety eight neonates of 30-41 weeks gestational age were studied by daily ultrasonography until ductus venosus closure.Results-In neonates of 30-33 weeks gestational age, the ductus venosus closed at 6.0 (2.4)days (mean (SD)); in those of 34-36 weeks gestational age, it closed at 6.1 (2.8) days; and in those of 37-41 weeks gestational age, it closed at 4.2 (2.1) days. The effect of antenatal administration of corticosteroids on the time of closure was also investigated in neonates of 30-34 weeks gestational age. Closure occurred by 5.5 (2.4) days in the group given corticosteroids compared with 7.5 (2.1) days in the remainder.Conclusions-The ductus venosus closed sooner after birth in neonates of greater gestational age or higher birth weight. Antenatal corticosteroid administration had a significant effect in promoting closure.