Microbial hydroxylation of natural drimenic lactones
Microbial hydroxylation of natural drimenic lactones
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DOI：
10.1016/s0031-9422(99)00199-5
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发表时间：
1999-09-01
期刊：
影响因子：
3.8
通讯作者：
Ricard, L
中科院分区：
文献类型：
--
作者：
Maurs, M;Azerad, R;Ricard, L
与铅毛霉、黑曲霉或阿根霉孵育，可获得相应的3 -羟基衍生物。从异茶menin中还得到了已知的天然7 α羟基衍生物（futronolide），并通过对其乙酸衍生物的x射线晶体学研究确定了其结构。1999爱思唯尔科学有限公司版权所有。
Incubation of confertifolin and isodrimenin with Mucor plumbeus, Aspergillus niger or Rhizopus arrhizus gave in good yields the corresponding 3 beta-hydroxy derivatives. From isodrimenin, the known natural 7 alpha-hydroxy derivative (futronolide) was also obtained and its structure was definitely established by X-ray crystallographic study of its acetate derivative. (C) 1999 Elsevier Science Ltd. All rights reserved.