Point-of-care testing in private pharmacy and drug retail settings: a narrative review.
Point-of-care testing in private pharmacy and drug retail settings: a narrative review.
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DOI：
10.1186/s12879-023-08480-w
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发表时间：
2023-08-23
影响因子：
3.7
通讯作者：
Lewycka, Sonia
中科院分区：
文献类型：
--
作者：
Chan, Justine Tin Nok;Nguyen, Van;Tran, Thuy Ngan;Nguyen, Nam Vinh;Do, Nga Thi Thuy;Doorn, H. Rogier Van;Lewycka, Sonia
使用传染病快速诊断测试的护理点检测(POCT)可能会指导适当使用抗菌药，减少抗菌素耐药性，并节约医疗资源的使用。在药房和药店等私人零售场所实施POCT可以减轻公共医疗保健的负担。我们对低收入和中等收入国家(LMIC)的POCT研究进行了叙述性回顾，并探讨了POCT的摄取、对治疗的影响和实施的可行性。计算机检索MEDLINE/PubMed，检索词为MEDLINE/PubMed，内容为私人零售场所人员实施传染病POCT干预研究。数据由两名独立的审查员摘录和分析。在检索到的848项研究中，有23项纳入了综述。研究涉及疟疾(19/23)、疟疾和肺炎(3/23)或呼吸道感染(1/23)。共纳入9项随机对照研究、4项对照非随机研究、5项非对照干预研究、1项干预前研究、1项交叉干预研究和3项随机对照研究。学习质量较差。总体而言，研究表明POCT可以成功实施，通过遵守治疗指南等结果来衡量适当治疗的改善。尽管卫生工作者有一些担忧，但客户和商店提供者对在私人零售环境中实施POCT表示欢迎。审查产生的主要主题包括需要结构良好的培训和培训后认证，涵盖检测阴性患者的指导方针、综合废物管理、社区宣传和需求产生活动、提供者的财务薪酬和定价机制，以及与医疗保健和支助的正式联系。我们的审查发现，有证据表明，POCT可以在LMIC的私人零售环境中成功实施，但需要全面的协议。需要高质量的随机研究来了解用于疟疾以外的传染病的POCT。网上版载有补充材料，可在10.1186/s12879-023-08480-w查阅。
Point-of-care testing (POCT) using rapid diagnostic tests for infectious disease can potentially guide appropriate use of antimicrobials, reduce antimicrobial resistance, and economise use of healthcare resources. POCT implementation in private retail settings such as pharmacies and drug shops could lessen the burden on public healthcare. We performed a narrative review on studies of POCTs in low- and middle-income countries (LMICs), and explored uptake, impact on treatment, and feasibility of implementation. We searched MEDLINE/PubMed for interventional studies on the implementation of POCT for infectious diseases performed by personnel in private retail settings. Data were extracted and analysed by two independent reviewers. Of the 848 studies retrieved, 23 were included in the review. Studies were on malaria (19/23), malaria and pneumonia (3/23) or respiratory tract infection (1/23). Nine randomised controlled studies, four controlled, non-randomised studies, five uncontrolled interventions, one interventional pre-post study, one cross-over interventional study and three retrospective analyses of RCTs were included. Study quality was poor. Overall, studies showed that POCT can be implemented successfully, leading to improvements in appropriate treatment as measured by outcomes like adherence to treatment guidelines. Despite some concerns by health workers, customers and shop providers were welcoming of POCT implementation in private retail settings. Main themes that arose from the review included the need for well-structured training with post-training certification covering guidelines for test-negative patients, integrated waste management, community sensitization and demand generation activities, financial remuneration and pricing schemes for providers, and formal linkage to healthcare and support. Our review found evidence that POCT can be implemented successfully in private retail settings in LMICs, but comprehensive protocols are needed. High-quality randomised studies are needed to understand POCTs for infectious diseases other than malaria. The online version contains supplementary material available at 10.1186/s12879-023-08480-w.
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DOI：
10.1016/j.rcsop.2021.100007
发表时间：
2021-03
期刊：
EXPLORATORY RESEARCH IN CLINICAL AND SOCIAL PHARMACY
影响因子：
--
作者：
Kherghehpoush, Sorosh;Mckeirnan, Kimberly C.
通讯作者：
Mckeirnan, Kimberly C.
影响因子：
2.8
作者：
Hutchinson E;Chandler C;Clarke S;Lal S;Magnussen P;Kayendeke M;Nabirye C;Kizito J;Mbonye A
通讯作者：
Mbonye A
影响因子：
5.2
作者：
Shelus, Victoria;Mumbere, Nobert;Mulogo, Edgar M.;Barrington, Clare;Baguma, Emmanuel;Muhindo, Rabbison;Herrington Jr, James E.;Emch, Michael;Maman, Suzanne;Boyce, Ross M.
通讯作者：
Boyce, Ross M.
影响因子：
3.7
作者：
Cohen J;Fink G;Berg K;Aber F;Jordan M;Maloney K;Dickens W
通讯作者：
Dickens W
影响因子：
5.4
作者：
Chandler, Clare I. R.;Hall-Clifford, Rachel;Asaph, Turinde;Pascal, Magnussen;Clarke, Sian;Mbonye, Anthony K.
通讯作者：
Mbonye, Anthony K.