Frictional properties of physically cross-linked PVA hydrogels as artificial cartilage
Frictional properties of physically cross-linked PVA hydrogels as artificial cartilage
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DOI：
10.1016/j.bsbt.2016.02.002
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发表时间：
2016-03
影响因子：
--
通讯作者：
Saori Sasaki;T. Murakami;A. Suzuki
中科院分区：
文献类型：
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作者：
Saori Sasaki;T. Murakami;A. Suzuki
物理交联的聚乙烯醇凝胶（冻融聚乙烯醇凝胶和铸干聚乙烯醇凝胶）被用作生物相容性材料，因为在制备过程中没有使用特殊化学品。因此，由于其优异的摩擦性能，铸干聚乙烯醇凝胶作为人工软骨的候选材料是有希望的。本研究制备并分析了冻融凝胶、铸干凝胶和混合凝胶三种类型的凝胶，混合凝胶是由铸干层和冻融层组成的叠层凝胶。通过往复试验考察了这三种聚乙烯醇水凝胶的摩擦行为。进一步研究了乙醇灭菌对聚乙烯醇水凝胶摩擦行为的影响。
Physically cross-linked PVA gels (freeze-thawed PVA gel and cast-dried PVA gel) are used as biocompatible materials since special chemicals were not used in their preparation. Cast-dried PVA gels are therefore promising as candidate materials for artificial cartilage because of their excellent frictional property. In this study, three types of gels-freeze-thawed gels, cast-dried gels and hybrid gels which are laminated gels consisting of both cast-dried layer and freeze-thawed layer were prepared and analyzed. The frictional behaviors of these three PVA hydrogels were examined in reciprocating test. Further, the effects of sterilization with ethanol on frictional behaviors of these PVA hydrogels were evaluated.