The human hippocampus observed by scanning electron microscopy (SEM): the dentate gyrus is made of an array of the neuronal lamellae.
The human hippocampus observed by scanning electron microscopy (SEM): the dentate gyrus is made of an array of the neuronal lamellae.
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扫描电子显微镜（SEM）观察到的人类海马：齿状回由神经元片层阵列组成。
DOI：
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
M. Kishibe
中科院分区：
文献类型：
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作者：
R. Kominami;H. Shinohara;S. Yasutaka;M. Kishibe
用扫描电镜观察了人海马的三维结构，冠状面组织切片显示多形层呈L形。上级肢与下肢外侧三分之二形成连续的板状结构。该板由L形条组成，这些条与边界并排融合，尽管不完全，但由颗粒层划界。下肢内侧三分之一是这些L形杆的独立部分，并参与了牙齿的形成。有40至50个齿状突，每个齿状突都有节段性血管。因此，多形层呈节段性排列，数量为40 ~ 50个，沿前后轴沿着排列，CA 4被L形多形层包围，并有上级和下脚。下丘脑内侧端被内侧1/3的多形性组织包裹，与邻近组织完全独立。因此，CA 4也可以按照与多形态层的条相同的计划分段地构造。这些观察结果表明，第一，三个主要组成部分的海马，颗粒层，多态层，和CA 4，是基于相同的板层单位在齿状回，和，第二，个别lamebrays出现不同的酒吧在内侧三分之一，但形成一个板在外侧三分之二的这些结构。下托内有7 ~ 12个由中央突及其覆盖物组成的锥形丘。丘状体中的锥体细胞极性明显，细胞顶端朝向中央突起，基部朝向周围。轴突从细胞基部发出，形成肺泡。锥体丘引起轻微的波的海马体的外侧边缘，但不影响的上级表面上的皮层。功能方面的节段性安排的神经元单位沿着前后轴和他们的中间-外侧的多样性进行了讨论，在海马的三突触通路。
Scanning electron microscopy (SEM) was employed to clarify the three dimensional structure of the human hippocampus.The polymorphic layer was L-shaped in coronal histological sections. The superior limb and lateral two thirds of the inferior limb formed a continuous plate. This plate consisted of L-shaped bars that were fused side by side with borders that were, although incompletely, demarcated by the stratum granulosum. The medial one third of the inferior limb was independent part of these L-shaped bars and took part in formation of the dentes. There were 40 to 50 dentes, and each had segmental blood vessels. Thus, the polymorphic layer was organized on a segmental plan, 40- 50 in number, arrayed along the antero-posterior axis.CA4 was surrounded by the L-shaped polymorphic layer and also had the superior and inferior crura. The medial end of the inferior crus was enveloped by the medial one third of the polymorphic tissue and was completely independent from its neighbors. Therefore, CA4, too, may be segmentally constructed following the same plan as the bars of the polymorphic layer. These observations suggest that, first, three major components of the hippocampus, the stratum granulosum, polymorphic layer, and CA4, are constructed based on the same lamellar unit in the dentate gyrus, and, second, the individual lamellae appear as distinct bars in the medial one third, but form a plate in the lateral two thirds of these structures. There were 7 to 12 pyramidal hillocks, organized of the central process and its covering, in the subiculum. Pyramidal cells showed clear polarity in the hillock; the cell apex oriented to the central process and the base to the periphery. The axon emitted from the cell base and formed the alveus. Pyramidal hillocks caused slight waves of the stratum pyramidale on the lateral border of the hippocampus but did not affect the superior surface. Functional aspects of the segmental arrangement of neuronal units along the antero-posterior axis and their medio-lateral diversity were discussed in terms of the three-synapse pathway in the hippocampus.