DNA bridging: a property shared among H-NS-like proteins

DNA bridging: a property shared among H-NS-like proteins
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DOI:
10.1128/jb.187.5.1845-1848.2005
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发表时间:
2005-03-01
影响因子:
3.2
通讯作者:
Wuite, GJL
Wuite, GJL
中科院分区:
生物学3区
文献类型:
--
作者:
Dame, RT;Luijsterburg, MS;Wuite, GJL

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类核相关蛋白 H-NS 被认为在大肠杆菌细菌染色质的组织中发挥重要作用。在大多数革兰氏阴性细菌中都发现了同源物,通常序列同一性非常低。显微镜分析表明,尽管序列同一性有限,但它们的结构组织导致了相似的 DNA 结合特性。
The nucleoid-associated protein H-NS is thought to play an essential role in the organization of bacterial chromatin in Escherichia coli. Homologues, often with very low sequence identity, are found in most gram-negative bacteria. Microscopic analysis reveals that, despite limited sequence identity, their structural organization results in similar DNA binding properties.