Palladium(II)-Catalyzed Direct Alkenylation of Nonaromatic Enamides
Palladium(II)-Catalyzed Direct Alkenylation of Nonaromatic Enamides
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DOI：
10.1021/ol301249n
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发表时间：
2012-07-06
期刊：
影响因子：
5.2
通讯作者：
Gillaizeau, Isabelle
中科院分区：
文献类型：
--
作者：
Gigant, Nicolas;Gillaizeau, Isabelle
通过钯 (II) 催化的 C-H 官能化实现了一种温和有效的非芳香族烯酰胺直接烯基化方法。反应范围包括环状和无环烯酰胺以及一系列活化烯烃。该方法代表了非芳香族环状烯酰胺的首次成功的直接C(3)-官能化。
A mild and efficient method for the direct alkenylation of nonaromatic enamides was achieved through a palladium(II)-catalyzed C-H funclionalization. The reaction scope includes cyclic and acyclic enamides and a range of activated alkenes. This approach represents the first successful direct C(3)-functionalization of nonaromatic cyclic enamides.