Avascular necrosis of bone in severe acute respiratory syndrome
Avascular necrosis of bone in severe acute respiratory syndrome
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DOI：
10.1016/j.crad.2003.12.008
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发表时间：
2004-07-01
影响因子：
2.6
通讯作者：
Du, XK
中科院分区：
文献类型：
--
作者：
Hong, N;Du, XK
目的：报告严重急性呼吸综合征（SARS）患者股骨头坏死（AVN）的发生率。 材料与方法：2003年3月至2003年5月间出现大关节疼痛的67例SARS患者于同一天接受X线平片和磁共振成像（MRI）检查。所有患者均接受类固醇和利巴韦林治疗。所有平片和磁共振图像均由两名经验丰富的肌肉骨骼放射科医生进行分析。对病变的任何异常、位置、范围、形态、数量、大小和信号强度进行评估。 结果：28 名患者被确诊为 AVN，诊断 AVN 的平均时间为 SARS 发病后 119 天，或使用类固醇后 116 天。双侧股骨头早期AVN 3例，一侧股骨头4例，双侧髋关节和膝关节5例，同侧髋关节和膝关节4例，膝关节10例，右侧腓骨近端1例，膝距骨1例。髋、膝、踝平片结果均为阴性。结论：SARS患者可发生AVN。 AVN 与类固醇的使用有很强的相关性。需要更多的研究来证实病毒本身是否也会导致 AVN。 (C) 2004 年皇家放射科医生学院。由爱思唯尔有限公司出版。保留所有权利。
AIM: To report the incidence of avascular osteonecrosis (AVN) in severe acute respiratory syndrome (SARS) patients.MATERIALS AND METHODS: Sixty-seven SARS patients who had Large joint pain between March 2003 and May 2003 underwent both plain radiographs and magnetic resonance imaging (MRI) examination on the same day. ALL patients received steroids and ribavirin treatment. All plain radiographs and MR images were analysed by two experienced musculoskeletal radiologists. Any abnormalities, location, extent, morphology, the number, size and signal intensity of lesions were evaluated.RESULTS: Twenty-eight patients were identified with AVN, The mean time to diagnosis of AVN was 119 days after the onset of SARS, or 116 days after steroid use. Three patients had early bilateral AVN of the femoral, head, four patients of one femoral head, five patients of the bilateral hips and knees, four patients of the ipsilateral hip and knees, 10 patients of the knee(s), one patient of the right proximal fibula, and one patient of the knees and talus. Results of hip, knee and ankle plain radiographs were negative.CONCLUSION: AVN can occur in the patients with SARS. AVN had a strong association with steroid use. More studies are required to confirm whether the virus itself can also lead to AVN. (C) 2004 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.