Validation of the Kihon Checklist and the frailty screening index for frailty defined by the phenotype model in older Japanese adults.

Validation of the Kihon Checklist and the frailty screening index for frailty defined by the phenotype model in older Japanese adults.
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DOI:
10.1186/s12877-022-03177-2
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发表时间:
2022-06-03
期刊:
影响因子:
4.1
通讯作者:
Kimura, Misaka
Kimura, Misaka
中科院分区:
医学2区
文献类型:
--
作者:
Watanabe, Daiki;Yoshida, Tsukasa;Watanabe, Yuya;Yamada, Yosuke;Miyachi, Motohiko;Kimura, Misaka

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“虚弱”一词可能看起来很简单,但不同研究用于评估它的方法有所不同。因此,根据所使用的衰弱评估方法,衰弱分类和预测能力存在不一致。我们的目的是检查几种日本老年人表型模型定义的衰弱筛查工具的诊断准确性。这项横断面研究纳入了 1,306 名年龄≥65 岁的日本老年人,作为日本京都-龟冈研究的一部分,他们通过整群随机抽样进行了身体检查。我们使用修订后的日本版心血管健康研究标准作为参考标准,评估了几种衰弱筛查仪器的诊断准确性。这些标准基于弗里德表型模型,包括五个要素:无意的体重减轻、虚弱(握力)、疲惫、缓慢(正常步态速度)和低体力活动。使用邮寄调查评估 Kihon 检查表 (KCL)、衰弱筛查指数 (FSI) 和自我报告的健康状况。我们根据参考标准计算了几种筛选工具的受试者工作特征曲线下的非参数面积 (AUC ROC)。参与者的平均(标准差)年龄为 72.8(5.5)岁。根据 Fried 表型模型,女性虚弱患病率为 12.2%,男性虚弱患病率为 10.3%。 KCL 的 AUC ROC 为 0.861(95% 置信区间:0.832–0.889),FSI 为 0.860(0.831–0.889),自我报告健康状况为 0.668(0.629–0.707)。识别体弱个体的临界点是 KCL 中 ≥ 7 分和 FSI 中 ≥ 2 分。我们的结果表明,基于日本老年人的表型模型,这两种仪器(KCL 和 FSI)对衰弱具有足够的诊断准确性。这可能有助于及早发现高危老年人的虚弱状况。
The term “frailty” might appear simple, but the methods used to assess it differ among studies. Consequently, there is inconsistency in the classification of frailty and predictive capacity depending on the frailty assessment method utilised. We aimed to examine the diagnostic accuracy of several screening tools for frailty defined by the phenotype model in older Japanese adults. This cross-sectional study included 1,306 older Japanese adults aged ≥ 65 years who underwent physical check-up by cluster random sampling as part of the Kyoto-Kameoka Study in Japan. We evaluated the diagnostic accuracy of several screening instruments for frailty using the revised Japanese version of the Cardiovascular Health Study criteria as the reference standard. These criteria are based on the Fried phenotype model and include five elements: unintentional weight loss, weakness (grip strength), exhaustion, slowness (normal gait speed), and low physical activity. The Kihon Checklist (KCL), frailty screening index (FSI), and self-reported health were evaluated using mailed surveys. We calculated the non-parametric area under the receiver operating characteristic curve (AUC ROC) for several screening tools against the reference standard. The participants’ mean (standard deviation) age was 72.8 (5.5) years. The prevalence of frailty based on the Fried phenotype model was 12.2% in women and 10.3% in men. The AUC ROC was 0.861 (95% confidence interval: 0.832–0.889) for KCL, 0.860 (0.831–0.889) for FSI, and 0.668 (0.629–0.707) for self-reported health. The cut-off for identifying frail individuals was ≥ 7 points in the KCL and ≥ 2 points in the FSI. Our results indicated that the two instruments (KCL and FSI) had sufficient diagnostic accuracy for frailty based on the phenotype model for older Japanese adults. This may be useful for the early detection of frailty in high-risk older adults.
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