Smoking-related Lung Disease
Smoking-related Lung Disease
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DOI：
10.1097/rti.0b013e3181c1abb7
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发表时间：
2009-11-01
影响因子：
3.3
通讯作者：
Franks, Teri J.
中科院分区：
文献类型：
--
作者：
Galvin, Jeffrey R.;Franks, Teri J.
引起临床关注的呼吸困难吸烟者除了表现出肺郎格罕细胞组织细胞增生症的改变外，还表现出肺气肿、气道炎症和纤维化的不同组合。人们也越来越多地接受香烟烟雾与肺泡壁纤维化之间的联系。急性嗜酸性粒细胞性肺炎是一个戏剧性的反应，最近发生的吸烟见于少数人。导致吸烟者肺部炎症和纤维化的相互关联的途径正在慢慢成为焦点。
Dyspneic smokers who come to clinical attention demonstrate varying combinations of emphysema, airway inflammation, and fibrosis in addition to the changes of pulmonary Langerhans' cell histiocytosis. There is also growing acceptance of a link between cigarette smoke and alveolar wall fibrosis. Acute eosinophilic pneumonia is a dramatic response to recent-onset smoking seen in a small number of individuals. The interconnected pathways that lead to lung inflammation and fibrosis in cigarette smokers are slowly coming into focus.